Skip to main content

Food-borne illness

Clostridium perfringens food poisoning

Clostridium perfringens is a spore-forming bacterium that causes outbreaks of diarrhoea and stomach cramps, typically after large batches of cooked meat, poultry or gravy are left to cool slowly or are kept at unsafe temperatures. Most cases are short-lived, but outbreaks in care homes and catered events can affect many people at once.

Last checked: 2026-10-03

Key facts

At a glance.

  • Cause

    A bacterium whose spores survive cooking, then multiply in food left at warm temperatures and release a toxin in the gut.

  • Typical foods

    Poultry, beef, pork and gravy, especially cooked in large batches.

  • Symptoms

    Diarrhoea and stomach cramps.

  • Settings

    Hospitals, schools, prisons, care homes and large catered events.

  • Prevention

    Keep cooked food hot or chill it promptly, and reheat thoroughly.

How an ordinary roast becomes a problem

Clostridium perfringens produces spores with a protective coat, which means they can survive normal cooking. After a dish has been cooked, the spores germinate if the food stays warm for long enough, and the bacteria multiply rapidly. When contaminated food is eaten, the bacteria produce a toxin in the intestine that causes illness.

The US Centers for Disease Control and Prevention links outbreaks mainly with poultry, beef, pork and gravy prepared in large batches and held at unsafe temperatures. This is why the illness is so closely associated with catering rather than with home cooking of single portions.

What the illness looks like

The characteristic picture is watery diarrhoea with stomach cramps. Vomiting and fever are not usually prominent, which helps to distinguish it from several other food-borne infections. The NHS describes food poisoning in general as causing feeling or being sick, diarrhoea, tummy pain, a high temperature and feeling generally unwell, symptoms that usually settle within a week.

Because many people eat the same dish, illness often affects a cluster of diners who became unwell at around the same time, which is a clue to environmental health officers investigating an outbreak.

Who is more likely to be affected

Healthy adults tend to recover without treatment. The NHS identifies infants, older adults and people with weakened immunity as higher-risk groups for food poisoning generally. Outbreaks of this particular organism occur predominantly in institutions such as hospitals, school canteens, prisons, nursing homes and large events, where food is cooked in bulk and may be kept warm for a long time before serving. The CDC notes that outbreaks peak in the cooler months around holiday meals.

Looking after yourself at home

The NHS advises resting, taking small and frequent sips of fluid to avoid dehydration, continuing to feed babies as usual, and using paracetamol for discomfort. Fruit juice, fizzy drinks and anti-diarrhoea medicines are not recommended for children under 12. Pharmacists can supply oral rehydration sachets and, for adults, loperamide.

  • Drink little and often rather than large amounts at once.

  • Eat bland food when you feel able.

  • Stay at home and wash hands thoroughly to avoid spreading illness; the NHS suggests staying off for at least two days after symptoms stop for diarrhoea and vomiting bugs.

  • Do not prepare food for others while unwell.

When to get medical advice

NHS 111 can advise if there are signs of dehydration, persistent vomiting, blood in the stool, diarrhoea lasting more than seven days or vomiting more than two days. Call 999 or go to A&E for vomiting blood, a severe headache with a stiff neck, severe abdominal pain, difficulty breathing or confusion. Diagnosis is usually clinical, but stool tests can be sent in an outbreak so that the cause can be confirmed.

Preventing outbreaks in kitchens and at home

Because spores survive cooking, prevention depends on controlling temperature afterwards. The CDC emphasises keeping food at safe temperatures. Practical steps include cooling large joints and pots quickly by dividing them into shallow containers, storing leftovers in the fridge soon after the meal, reheating until steaming hot throughout, and serving hot dishes straight away rather than leaving them on a counter.

The World Health Organization encourages the Five Keys to Safer Food: keep clean, separate raw and cooked, cook thoroughly, keep food at safe temperatures and use safe water and raw materials.

Frequently asked

Questions people ask.

Quick, plain-English answers to the questions we hear most.

  • How soon do symptoms begin?

    The NHS says food poisoning symptoms usually develop within hours to days, and occasionally take weeks, so timing alone does not identify the organism.

  • How long does it last?

    Food poisoning usually gets better within a week according to the NHS. Seek advice if diarrhoea continues beyond seven days.

  • Do I need antibiotics?

    Antibiotics are not usually part of self-care for food poisoning, and the toxin-mediated illness settles by itself. Fluids and rest are the mainstay.

  • Can I catch it from another person?

    It is not typically spread from person to person. Illness comes from eating contaminated food, although good hand hygiene remains sensible.

  • Why does gravy keep appearing in outbreaks?

    Large pots of gravy and meat dishes cool slowly and are often held warm for hours, giving spores time to germinate and multiply.

  • Does reheating make food safe?

    Thorough reheating destroys many bacteria, but it is better to avoid slow cooling and long warm holding in the first place.

  • Is it the same as Bacillus cereus poisoning?

    They are different organisms, although both form spores and are linked with cooked food kept at poor temperatures.

  • Who should seek help early?

    Babies, older adults, pregnant women and people with weakened immunity should seek advice sooner if they become dehydrated or unwell.

  • Should an outbreak be reported?

    Clusters of illness after a shared meal are usually reported to local environmental health teams so the source can be investigated.

  • Can I eat leftovers safely?

    Yes, if they were cooled promptly, kept in the fridge and reheated until steaming hot all the way through.

Where this comes from

Sources and checking.

This guide is for information, not medical advice.

Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.

Published 2026-10-03, next review 2027-10-03.