Infections and vaccination
Diphtheria: symptoms, how it spreads, treatment and vaccination
Diphtheria is a contagious bacterial infection of the nose and throat, and sometimes the skin. It is rare in the UK because children are routinely vaccinated, but it can be serious and sometimes fatal if not treated quickly. Symptoms include a thick grey-white throat coating, fever, sore throat and swollen neck glands. Treatment is antibiotics and antitoxin; call your GP surgery or NHS 111 if you have symptoms after travel.
Last checked: 2026-10-11
Key facts
At a glance.
-
What it is
The NHS says diphtheria is a contagious infection that affects the nose and throat, and sometimes the skin.
-
How common
Rare in the UK, because babies and children have been routinely vaccinated since the 1940s, though there is a small risk if you travel to some parts of the world.
-
How it spreads
By coughs and sneezes, close contact with an infected person, or sharing items such as cups, cutlery, clothing or bedding.
-
Symptoms
A thick grey-white coating on the throat, nose and tongue, fever, sore throat, swollen neck glands, and difficulty breathing and swallowing.
-
Incubation
The NHS says symptoms usually start 2 to 5 days after infection.
-
Treatment
Antibiotics, medicines that stop the effects of the toxins, and cleaning infected wounds. Treatment usually lasts 2 weeks.
-
Prevention
Vaccination: 4 doses of the 6-in-1 vaccine, the 4-in-1 pre-school booster and the 3-in-1 teenage booster.
What is diphtheria?
The NHS describes diphtheria as a contagious bacterial infection that affects the nose and throat, and sometimes the skin. UKHSA’s Green Book chapter says it is an acute infectious disease of the upper respiratory tract, and occasionally the skin, caused by diphtheria toxin produced by toxigenic Corynebacterium diphtheriae or Corynebacterium ulcerans.
The NHS says it can be a serious illness and sometimes fatal, especially in children, if not treated quickly, and that vaccination can prevent it.
What are the symptoms of diphtheria?
According to the NHS, diphtheria of the throat and nose causes the symptoms below, which usually start 2 to 5 days after becoming infected.
-
A thick grey-white coating that may cover the back of the throat, nose and tongue.
-
A high temperature (fever).
-
A sore throat.
-
Swollen glands in the neck.
-
Difficulty breathing and swallowing.
Skin (cutaneous) diphtheria
The NHS says that in places with poor hygiene, infection of the skin is more common. Cutaneous diphtheria can cause pus-filled blisters on the legs, feet and hands, and large ulcers surrounded by red, sore-looking skin. Skin ulcers usually heal within 2 to 3 months but may leave a scar.
How does diphtheria spread? Is it contagious?
Yes. The NHS says diphtheria is a contagious bacterial infection spread by coughs and sneezes, or through close contact with someone who is infected. You can also get it by sharing items such as cups, cutlery, clothing or bedding with an infected person.
It can spread to others easily, so if you think you may have it, call your GP surgery before you go in; they may suggest talking over the phone.
How is diphtheria treated?
The NHS lists the main treatments as antibiotics to kill the diphtheria bacteria, medicines that stop the effects of the harmful substances (toxins) produced by the bacteria, and thoroughly cleaning any infected wounds if the skin is affected. Treatment usually lasts 2 weeks.
People who have been in close contact with someone who has diphtheria will also need antibiotics and may be given the diphtheria vaccine. The NHS says a contact tracing team will get in touch with anyone who needs to be treated.
The diphtheria vaccine and UK schedule
The NHS says diphtheria is rare in the UK because babies and children have been routinely vaccinated since the 1940s. Protection comes from a combined vaccine at several ages.
| Age | Vaccine | Doses |
|---|---|---|
| 8, 12 and 16 weeks, and 18 months | 6-in-1 vaccine | 4 separate doses |
| 3 years 4 months | 4-in-1 pre-school booster | 1 booster |
| 14 years (school year 9, around 13 to 14) | 3-in-1 teenage booster (Td/IPV) | 1 booster |
Diphtheria and travel
The NHS says the best way to avoid diphtheria while travelling is to be fully vaccinated. If you travel to a part of the world where there may be a risk, you may need a booster if you were last vaccinated more than 10 years ago. It lists Africa, South America, India, south east Asia and eastern Europe as parts of the world where there may be a risk, and says that places with higher cases change over time, so check the TravelHealthPro country guides.
You may be able to get a combined diphtheria, tetanus and polio vaccine free on the NHS; ask at your GP surgery.
When to get medical help
The NHS says to ask for an urgent GP appointment or get help from NHS 111 if you have travelled to a country where diphtheria is found and have diphtheria symptoms, or you have been in close contact with someone who has diphtheria. Call your GP surgery before going in.
If you have symptoms while travelling, get medical help as soon as possible rather than waiting until you get back to the UK. Call 999 if someone has severe difficulty breathing.
NHS and private pathways in general terms
Childhood diphtheria vaccination is part of the NHS schedule and is free. Adult boosters for travel are arranged through a GP practice or private travel clinic; the NHS says a combined vaccine may be free, so ask your practice. Suspected diphtheria is managed by NHS services, with public health teams handling contact tracing.
Frequently asked
Questions people ask.
Quick, plain-English answers to the questions we hear most.
-
What is diphtheria?
A contagious bacterial infection affecting the nose and throat and sometimes the skin. The NHS says it can be serious and sometimes fatal, especially in children, if not treated quickly.
-
What are the symptoms of diphtheria?
A thick grey-white coating at the back of the throat, nose and tongue, fever, sore throat, swollen neck glands and difficulty breathing and swallowing. Symptoms usually start 2 to 5 days after infection.
-
Is diphtheria still around in the UK?
It is rare in the UK because of routine childhood vaccination since the 1940s, the NHS says, though there is a small risk if you travel to some parts of the world.
-
How is diphtheria spread?
By coughs and sneezes or close contact with an infected person, and by sharing items such as cups, cutlery, clothing or bedding.
-
How is diphtheria treated?
With antibiotics, medicines that stop the effects of the toxins, and cleaning infected wounds. The NHS says treatment usually lasts 2 weeks.
-
Which vaccines protect against diphtheria?
The 6-in-1 vaccine for babies, the 4-in-1 pre-school booster and the 3-in-1 teenage booster protect against diphtheria, per the NHS schedule.
-
Do I need a booster before travelling?
You may need one if you are going to a part of the world with diphtheria and were last vaccinated more than 10 years ago. The NHS says check TravelHealthPro and ask your GP surgery.
-
Can adults get diphtheria?
The NHS describes diphtheria as a risk to people who are not fully vaccinated, especially when travelling. It says it can be serious and sometimes fatal, especially in children, if not treated quickly.
-
What is cutaneous diphtheria?
Diphtheria of the skin. The NHS says it is more common in places with poor hygiene and causes pus-filled blisters and large ulcers on the legs, feet and hands.
-
What should I do if I have been in contact with someone with diphtheria?
Ask for an urgent GP appointment or get help from NHS 111, calling your GP surgery before you go in. The NHS says close contacts may need antibiotics and may be given the vaccine.
Where this comes from
Sources and checking.
This guide is for information, not medical advice.
Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.
Published 2026-10-11, next review 2027-10-11.
-
NHS: Diphtheria, https://www.nhs.uk/conditions/diphtheria/ , retrieved October 2026
-
NHS: 6-in-1 vaccine, https://www.nhs.uk/vaccinations/6-in-1-vaccine/ , retrieved October 2026
-
NHS: Td/IPV vaccine (3-in-1 teenage booster), https://www.nhs.uk/vaccinations/td-ipv-vaccine-3-in-1-teenage-booster/ , retrieved October 2026
-
UK Health Security Agency: Diphtheria, the Green Book chapter 15, https://www.gov.uk/government/publications/diphtheria-the-green-book-chapter-15 , retrieved October 2026
Related guides
Keep reading.
-
Tetanus
Another disease covered by the same vaccines.
Read guide -
Polio
Covered by the 6-in-1 and booster vaccines.
Read guide -
Tonsillitis
A common cause of sore throat.
Read guide -
Croup
A childhood breathing and cough illness.
Read guide -
Measles
Another vaccine-preventable infection.
Read guide -
Travel vaccinations
How travel vaccines are arranged.
Read guide -
Vaccinations
Overview of vaccinations in the UK.
Read guide