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Skin conditions

Dyshidrotic eczema (pompholyx): treatment, causes and triggers

Dyshidrotic eczema, called pompholyx in the UK, is a type of eczema that causes itchy, fluid-filled blisters on the hands or feet. The NHS says it is usually long term but comes and goes, with flare-ups lasting 2 to 3 weeks. Daily emollients and short courses of steroid creams help, and a GP can refer you to a dermatologist if it is severe.

Last checked: 2026-10-11

Key facts

At a glance.

  • What it is

    The NHS says pompholyx (also called dyshidrotic eczema) is a type of eczema that affects the hands or feet.

  • Symptoms

    Itchy blisters on the hands or feet that come and go. The first symptom is often itchy skin with a burning or prickling feeling, then fluid-filled blisters appear.

  • How long it lasts

    The NHS says symptoms usually last 2 to 3 weeks at a time, and that it is usually a long-term condition that comes and goes. Treatment can help control the symptoms.

  • Contagious?

    No source used here suggests it spreads between people. The NHS says atopic eczema is not contagious, and describes pompholyx as a type of eczema; infected blisters need treatment.

  • Cause

    The NHS says it is not clear exactly what causes it. Things thought to trigger symptoms in some people include strong chemicals, nickel or cobalt sensitivity, wet hands, stress, heat and sweat.

  • Main treatments

    Daily emollients and topical steroids used for a few weeks at a time. A GP may suggest potassium permanganate soaks for leaking blisters.

  • When to see a GP

    If you think you have it, or the blisters are very painful, leak yellow or green pus or have a yellow-brown crust, which the NHS says are signs of infection.

How is dyshidrotic eczema (pompholyx) treated?

The NHS says the main treatments are moisturisers (emollients) used every day to stop the skin becoming dry, and steroid creams and ointments (topical steroids) used for a few weeks at a time to reduce irritation and soreness.

If the blisters leak fluid, the NHS says a GP may suggest soaking your skin in potassium permanganate solution, which helps dry the blisters and reduces the risk of infection. If the blisters become infected, a GP may prescribe antibiotics.

If symptoms are severe or treatment is not helping, a GP may refer you to a dermatologist. The NHS says a dermatologist may recommend steroid tablets, ultraviolet (UV) light treatment or other medicines such as alitretinoin, and will closely monitor progress.

NICE says alitretinoin is recommended for adults with severe chronic hand eczema that has not responded to potent topical corticosteroids. Only dermatologists, or physicians with experience in managing severe chronic hand eczema and systemic retinoids, should start and monitor it.

Do not burst the blisters, says the NHS. If itching is disturbing your sleep, a pharmacist can advise about sedating antihistamines taken before bed.

Treatment steps for pompholyx, as set out by the NHS and NICE
StepTreatmentWho arranges it
Every dayEmollients (moisturisers); emollient soap substituteYou, with pharmacist advice
Flare-upsTopical steroids for a few weeks at a timeGP
Leaking blistersPotassium permanganate soaksGP suggestion
InfectionAntibioticsGP
Severe or not respondingSteroid tablets, UV light, alitretinoinDermatologist, after GP referral

What causes dyshidrotic eczema, and what are the triggers?

The NHS says it is not clear exactly what causes pompholyx. Certain things are thought to cause symptoms in some people, and the NHS says that if you notice something causes your symptoms, avoiding it as much as possible may help.

  • Contact with strong chemicals such as soaps, cleansers and detergents.

  • An allergy or sensitivity to certain metals, such as nickel or cobalt.

  • Getting your hands wet regularly, for example if you are a hairdresser.

  • Stress.

  • Heat and sweat.

Does diet matter?

The NHS list of things thought to bring on pompholyx does not include foods, and the sources used for this page do not give dietary advice. If you suspect a food or a metal such as nickel is involved, raise it with your GP rather than cutting foods out on your own. The NHS contact dermatitis page says a GP can refer you to a dermatologist for further tests if the substance causing a reaction cannot be identified.

What are the symptoms?

The NHS says the first symptom is often itchy skin with a burning or prickling feeling in the affected area. Fluid-filled blisters then appear. They are usually very itchy and may leak fluid, and may look darker on black or brown skin.

When the blisters go away, the skin may be dry, cracked and sore, and sometimes it bleeds.

Pompholyx most often affects the fingers and palms of the hands. It can also affect the toes and soles of the feet.

How long does a flare-up last?

The NHS says symptoms usually last 2 to 3 weeks at a time. It describes pompholyx as usually a long-term condition that comes and goes over time, and says treatment can help control the symptoms.

Is dyshidrotic eczema contagious?

The NHS describes pompholyx as a type of eczema with a range of possible triggers, and says that atopic eczema is not contagious so you cannot catch or spread it. Nothing in the NHS pompholyx page suggests it spreads between people.

The blisters can become infected, which is a different matter: the NHS lists blisters that are very painful, leak yellow or green pus or are covered in a yellow-brown crust as signs of infection.

Conditions that can look similar

The NHS says other conditions can cause sore, itchy patches or blisters on the hands and feet, including psoriasis and fungal infections like ringworm and athlete's foot. It says not to try to diagnose yourself and to see a GP if you are worried.

Conditions the NHS lists as able to cause itchy patches or blisters on the hands and feet
ConditionWhat the NHS says
PompholyxItchy, fluid-filled blisters on hands or feet that come and go; usually last 2 to 3 weeks at a time
Contact dermatitisA type of eczema triggered by contact with a particular substance; can be itchy, blistered, dry and cracked, most commonly on the hands and face
PsoriasisCan cause sore, itchy patches on the hands and feet
Ringworm and athlete's footFungal infections that can also cause itchy patches or blisters

Looking after your skin day to day

The NHS says your skin may get irritated easily, and suggests the following.

  • Wash your hands with warm (not hot or cold) water and use an emollient soap substitute instead of regular soap.

  • Wear protective gloves, ideally with a cotton lining, when using chemicals like shampoos, cleansers and detergents.

  • Wear socks, tights or stockings made from cotton or silk rather than nylon.

  • Wear shoes made from leather rather than plastic or rubber.

  • Avoid anything you think causes your symptoms.

  • The NHS contact dermatitis page adds that gloves should be taken off every now and again because sweating can make symptoms worse, and that emollients applied frequently and in large amounts help protect the skin.

When to see a GP

The NHS says to see a GP if you think you have pompholyx, if you have pompholyx and the blisters are very painful, leak yellow or green pus or are covered in a yellow-brown crust (signs of infection), or if you have any other changes to your skin you are worried about.

The NHS says a pharmacist can help with itching that affects your sleep.

NHS and private pathways in general terms

Most people are managed in primary care by a GP and pharmacist. Referral to NHS dermatology is for severe disease or disease not responding to treatment, and waiting times vary by area.

Private dermatology is also available, including assessment for contact allergy. Share your GP records and previous treatments so care stays consistent.

Frequently asked

Questions people ask.

Quick, plain-English answers to the questions we hear most.

  • Is dyshidrotic eczema the same as pompholyx?

    Yes. The NHS says pompholyx is also called dyshidrotic eczema. It is a type of eczema affecting the hands or feet.

  • What is the best treatment for dyshidrotic eczema?

    The NHS says the main treatments are daily emollients and topical steroids used for a few weeks at a time. A GP may suggest potassium permanganate soaks for leaking blisters, and a dermatologist may use steroid tablets, UV light or alitretinoin.

  • What causes dyshidrotic eczema?

    The NHS says it is not clear exactly what causes it. Strong chemicals, nickel or cobalt sensitivity, regularly wet hands, stress, and heat and sweat are thought to trigger symptoms in some people.

  • How long does a pompholyx flare-up last?

    The NHS says symptoms usually last 2 to 3 weeks at a time, and that the condition is usually long term and comes and goes.

  • Is pompholyx contagious?

    The NHS describes it as a type of eczema, and says atopic eczema is not contagious. Nothing in the NHS pompholyx page suggests you can catch it from someone, though blisters can become infected.

  • Should I pop the blisters?

    No. The NHS says not to burst your blisters.

  • How do I know if the blisters are infected?

    The NHS says blisters that are very painful, leak yellow or green pus or are covered in a yellow-brown crust are signs of infection. See a GP.

  • Can food trigger dyshidrotic eczema?

    The NHS list of triggers does not include food. The sources used here give no dietary advice, so speak to your GP before cutting out foods.

  • What else could it be?

    The NHS says psoriasis and fungal infections like ringworm and athlete's foot can also cause sore, itchy patches or blisters on the hands and feet, so do not diagnose yourself.

  • When might I be referred to a dermatologist?

    The NHS says if symptoms are severe or treatment is not helping, a GP may refer you to a skin specialist.

Where this comes from

Sources and checking.

This guide is for information, not medical advice.

Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.

Published 2026-10-11, next review 2027-10-11.