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Gynaecological cancers

Endometrial (womb) cancer: symptoms, causes and treatment

Endometrial cancer is the most common type of womb cancer and starts in the lining of the womb. It is most common after the menopause. The main symptom is vaginal bleeding, especially after the menopause, though changes to periods or discharge can also occur. See a GP promptly if you have symptoms. It is usually treatable when found early, mainly with surgery, sometimes radiotherapy or chemotherapy.

Last checked: 2026-10-11

Key facts

At a glance.

  • What it is

    The NHS says most womb cancer starts in the lining of the womb (endometrium), which is also known as endometrial cancer.

  • Who gets it

    It is most common in women who have been through the menopause, and anyone with a womb can get it.

  • How common

    Cancer Research UK says around 10,200 women are diagnosed each year in the UK, making it the 4th most common cancer in women.

  • Main symptom

    Vaginal bleeding, especially after the menopause, but also heavy periods unusual for you, bleeding between periods or changed discharge.

  • Biggest risk

    Cancer Research UK says being overweight or obese is one of the biggest risks in the UK; high oestrogen levels are a main factor.

  • Outlook

    The NHS says womb cancer is usually treatable when found early.

  • Treatment

    Surgery is often the main treatment; radiotherapy, chemotherapy, hormone therapy and immunotherapy may also be used.

What are the symptoms of endometrial cancer?

The NHS lists the main symptoms of womb cancer as bleeding or spotting from the vagina after the menopause, heavy periods that are unusual for you, vaginal bleeding between your periods, and a change to your vaginal discharge. Cancer Research UK says the most common symptom is abnormal bleeding from the vagina, especially in post-menopausal women.

Other symptoms the NHS lists are a lump or swelling in the tummy or pelvis, pain in the lower back or pelvis, pain during sex, and changes to how often you pee and poo.

These symptoms are common and can be caused by many conditions, so having them does not mean you have cancer, but the NHS says it is important to get them checked and not to wait.

What is endometrial cancer?

Cancer Research UK says womb cancer starts in the cells of the womb (uterus), and most start in the lining, the endometrium, so are called endometrial or uterine cancers. Most are adenocarcinomas, which start in the glands of the endometrium.

Most people who develop womb cancer are older women, and it is much less common in those younger than 40. Trans men and non-binary people assigned female at birth who have not had a hysterectomy can also develop it. The NHS says you cannot get womb cancer if you have had surgery to remove your womb.

What causes womb cancer and who is at risk?

The NHS says having a high level of the hormone oestrogen is one of the main things that can increase your chance of womb cancer. Cancer Research UK says being overweight or obese is one of the biggest risks in the UK.

Risk factors listed by the NHS
GroupExamples
Linked to high oestrogenBeing overweight; some types of hormone replacement therapy (HRT); never having given birth; polyendocrine metabolic ovarian syndrome (PMOS); going through the menopause after age 55.
Other factorsDiabetes; a family history of bowel, ovarian or womb cancer; Lynch syndrome; taking medicines such as tamoxifen; previous pelvic radiotherapy.

How is womb cancer diagnosed?

You usually start with your GP, who will ask about your health, family history and symptoms, may examine you and may refer you for tests or to a specialist. Tell the GP about any history of cancer or Lynch syndrome. The NHS says you may be offered an urgent referral if symptoms could be cancer, and that this does not definitely mean you have cancer.

Specialist tests can include a transvaginal scan, blood tests, hysteroscopy (a thin tube with a camera to look inside the womb) and a biopsy of the womb lining. The NHS says you should get results within a few weeks. If cancer is found you will usually have more tests such as CT, MRI or PET scans and a chest X-ray to establish the stage.

How is endometrial cancer treated?

The NHS says womb cancer is usually treatable when found early, and treatment depends on the size of the cancer, where it is, whether it has spread and your general health. It will usually include surgery, chemotherapy or radiotherapy, and may include targeted medicines.

Treatments for womb cancer (NHS)
TreatmentWhen it may be used
SurgeryOften the main treatment, especially if found early: removing the womb and cervix (hysterectomy), sometimes the ovaries, fallopian tubes and lymph nodes.
RadiotherapyAs the main treatment if you cannot have surgery, if the cancer is large or has spread, or after surgery to help stop it coming back.
ChemotherapyOn its own or with radiotherapy, after surgery, or to slow the cancer and ease symptoms if it has spread.
Hormone therapyTo ease symptoms or control cancer that has spread, if you are not well enough for surgery or radiotherapy.
ImmunotherapyMay be suitable for advanced womb cancer or if it has come back.

Can you lower your risk?

The NHS says you cannot always prevent womb cancer, but you can lower your chance by keeping to a healthy weight, staying active, eating a healthy balanced diet and talking to a GP about which HRT is best for you. If you have Lynch syndrome your care team will talk to you about reducing your risk.

When to see a GP

See a GP if you have any symptoms of womb cancer, particularly any vaginal bleeding after the menopause. The NHS says to try not to be embarrassed, as the doctor or nurse will be used to talking about these symptoms, and not to wait: finding it early can make it easier to treat.

NHS and private pathways in general terms

On the NHS you start with your GP, who can make an urgent suspected cancer referral; a clinical nurse specialist is your main point of contact during and after treatment. Private gynaecology services offer scans, hysteroscopy and surgery; if you use them, ask what is included and ensure results are shared with your GP.

Frequently asked

Questions people ask.

Quick, plain-English answers to the questions we hear most.

  • What is endometrial cancer?

    A cancer that starts in the lining of the womb (the endometrium). The NHS says most womb cancers are of this type, and it is most common after the menopause.

  • What are the symptoms of endometrial cancer?

    The main symptom is abnormal vaginal bleeding, especially after the menopause. The NHS also lists heavy or unusual periods, bleeding between periods and a change in discharge.

  • Is bleeding after the menopause always cancer?

    No. The NHS says these symptoms are common and can be caused by many conditions, but they must be checked by a GP. Finding cancer early makes it easier to treat.

  • What causes endometrial cancer?

    The NHS says high oestrogen levels are one of the main factors, linked to being overweight, some HRT, never having given birth and a late menopause.

  • How common is womb cancer?

    Cancer Research UK says around 10,200 women are diagnosed with womb cancer in the UK each year, making it the 4th most common cancer in women.

  • How is endometrial cancer diagnosed?

    Via a GP and then specialist tests. The NHS lists a transvaginal scan, blood tests, hysteroscopy and a biopsy of the womb lining.

  • How is endometrial cancer treated?

    Surgery is often the main treatment, especially if found early. The NHS says radiotherapy, chemotherapy, hormone therapy and immunotherapy may also be used depending on the cancer.

  • Can endometrial cancer be cured?

    The NHS says womb cancer is usually treatable when found early. Outlook depends on type, stage, grade and your general health, which your specialist team can explain.

  • Can I get womb cancer if I have had a hysterectomy?

    The NHS says you cannot get womb cancer if you have had surgery to remove your womb.

  • Can I lower my risk of womb cancer?

    You cannot always prevent it. The NHS suggests a healthy weight, regular exercise, a healthy diet, and talking to a GP about which HRT is best for you.

Where this comes from

Sources and checking.

This guide is for information, not medical advice.

Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.

Published 2026-10-11, next review 2027-10-11.