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Cancer

Oesophageal (esophageal) cancer: symptoms, causes, tests and treatment

Oesophageal (esophageal) cancer is cancer of the food pipe that connects the mouth to the stomach. Common symptoms include difficulty swallowing, heartburn that does not go away, and unexplained weight loss. These symptoms are often caused by other conditions, but see a GP to have them checked. Finding it early makes it more treatable.

Last checked: 2026-10-11

Key facts

At a glance.

  • What it is

    The NHS says oesophageal cancer is a cancer found anywhere in the oesophagus (gullet or food pipe), which connects the mouth to the stomach.

  • How common

    Cancer Research UK says around 9,500 people are diagnosed each year in the UK, and it is more common in men and in older people. Almost 45% of new cases are in people aged 75 and over.

  • Main symptoms

    Problems swallowing, heartburn or indigestion that does not go away, losing weight without trying, feeling or being sick, a cough that is not getting better, and pain in the throat or middle of the chest.

  • Two main types

    Squamous cell carcinoma, which tends to start in the upper and middle part, and adenocarcinoma, which tends to start in the lower part, according to Cancer Research UK.

  • Risk factors

    The NHS lists age over 75, being a man, long-term severe acid reflux, Barrett's oesophagus, being overweight, smoking and drinking too much alcohol.

  • Main test

    A gastroscopy with a biopsy. The NHS says you should get results of a gastroscopy and biopsy within 2 weeks.

  • Treatment

    Surgery, chemotherapy, radiotherapy, and targeted medicines and immunotherapy. The NHS says it is often treatable but can be difficult to treat.

What are the symptoms of oesophageal cancer?

The NHS says there are many possible symptoms of oesophageal cancer, but they might be hard to spot. They can affect digestion:

  • Problems swallowing (dysphagia).

  • Feeling or being sick.

  • Heartburn or acid reflux.

  • Symptoms of indigestion, such as burping a lot.

Other symptoms to watch for

The NHS lists these further symptoms. Cancer Research UK says difficulty swallowing is the most common symptom, which may feel like pain or a burning sensation when you swallow, or food sticking in the throat or chest.

  • A cough that is not getting better, or one that happens when you try to eat.

  • A hoarse voice.

  • Loss of appetite, or losing weight without trying to.

  • Feeling tired or having no energy.

  • Pain in the throat or the middle of the chest, especially when swallowing.

  • Black poo or coughing up blood (although these are uncommon).

When to see a GP, and when to get urgent help

The NHS says these symptoms are very common and can be caused by many different conditions, so having them does not definitely mean you have oesophageal cancer. But it is important to get them checked, because finding cancer early makes it more treatable.

If you have another condition such as acid reflux disease you may get symptoms regularly and get used to them. The NHS says it is important to be checked if your symptoms change, get worse or do not feel normal for you.

When to get help, from the NHS
SituationWhat to do
Problems swallowingSee a GP
Noticeable weight lossSee a GP
Heartburn most days that lasts for 3 weeks or moreSee a GP
Symptoms that are getting worse, or digestive symptoms not improving with usual treatmentSee a GP
Being sick for more than 2 days, or black or dark red pooAsk for an urgent GP appointment or get help from NHS 111
Worried but not sure where to get helpCall 111 or use 111 online

How is oesophageal cancer diagnosed?

The NHS says the GP may feel your neck and tummy and might arrange a blood test. If the GP thinks your symptoms could be cancer, you may get an urgent referral for more tests or to see a specialist. This does not definitely mean you have cancer.

The main test is a gastroscopy. A long, thin, flexible tube with a small camera is put into your mouth and down your oesophagus. A small sample of cells (a biopsy) may be taken and sent to a laboratory. The NHS says it should take around 10 to 15 minutes, and that you will probably be in hospital for several hours.

You may be offered a throat spray, sedation or, in some cases, a general anaesthetic. The NHS says you should get your results within 2 weeks.

If cancer is found, more tests find the size and how far it has spread (the stage). The NHS says you may need an ultrasound scan (sometimes from inside the body using an endoscope), a CT scan, a PET-CT scan, or a small operation to look inside the tummy called a laparoscopy.

How is oesophageal cancer treated?

The NHS says oesophageal cancer is often treatable but can be difficult to treat. Treatment depends on the size and type of cancer, where it is, whether it has spread, and your general health. Cancer Research UK says you might have one or more treatments.

The NHS says a specialist care team will explain the treatments, benefits and side effects, create a plan with you and help you manage side effects, including changes to your diet.

Treatments for oesophageal cancer, from the NHS and Cancer Research UK
TreatmentWhen it may be used
SurgeryIf found early and has not spread; the surgeon removes part, or in a small number of people most, of the oesophagus
ChemotherapyBefore surgery to shrink the cancer, after surgery to remove remaining cancer, with radiotherapy, or to control symptoms of advanced cancer
RadiotherapyTo treat early cancer, usually with chemotherapy, or to control symptoms of advanced cancer
Targeted medicines and immunotherapyIf it has spread, if it cannot be cured, or to lower the risk of coming back after surgery
Palliative careIf it cannot be cured, to limit the cancer and its symptoms and help you feel comfortable

Making swallowing easier

Cancer Research UK says swallowing can be difficult for some people with cancer in the oesophagus, and that there are treatments that can make swallowing easier. It also describes prehabilitation, things you can do to feel more in control before treatment.

What causes oesophageal cancer?

The NHS says it is not always clear what causes oesophageal cancer. Anyone can get it, but you might be more at risk if you are over 75 (it is not very common under 45), are a man, or have long-term, severe acid reflux (gastro-oesophageal reflux disease) or Barrett's oesophagus.

Many oesophageal cancers are linked to lifestyle: you are more likely to get it if you are overweight, smoke or drink too much alcohol.

The NHS says Barrett's oesophagus is a condition where some cells in the oesophagus grow abnormally. If you have it, you are slightly more likely to get oesophageal cancer, but this is not common.

Types of oesophageal cancer

Cancer Research UK says there are two main cell types lining the oesophagus, so two main types of cancer. The type affects the plan, along with the stage and grade.

Main types of oesophageal cancer, from Cancer Research UK
TypeWhere it tends to startCells involved
Squamous cell carcinomaUpper and middle part of the oesophagusCells that make up the inner lining
AdenocarcinomaLower part of the oesophagusGland cells
Gastro-oesophageal junction cancerWhere the oesophagus joins the stomachA separate type that can behave differently

Can you reduce your chance of oesophageal cancer?

The NHS says you cannot always prevent it, but healthy changes can lower your chances.

  • Try to lose weight if you are overweight.

  • Let hot drinks cool down a bit before drinking, so they do not damage your oesophagus.

  • Try to cut down on alcohol; the NHS says avoid drinking more than 14 units a week.

  • Try to quit smoking.

NHS and private pathways in general terms

On the NHS, suspected oesophageal cancer is usually investigated through an urgent GP referral and gastroscopy, followed by treatment planned by a specialist team with a clinical nurse specialist as your main point of contact.

Private gastroscopy and consultations are available, but confirmed cancers are normally treated by specialist multidisciplinary teams, and any private results should be shared with your GP so the NHS team has the full picture.

Frequently asked

Questions people ask.

Quick, plain-English answers to the questions we hear most.

  • What are the first signs of oesophageal cancer?

    The NHS says problems swallowing, feeling or being sick, heartburn or acid reflux and indigestion are the main digestive symptoms. Others include a cough that is not getting better, a hoarse voice, weight loss and chest pain.

  • Is difficulty swallowing always cancer?

    No. Cancer Research UK says a harmless narrowing called a stricture can also make swallowing difficult, but it is important to get this symptom checked by your doctor.

  • What causes oesophageal cancer?

    The NHS says it is not always clear. Risk factors include being over 75, being a man, long-term severe acid reflux, Barrett's oesophagus, being overweight, smoking and drinking too much alcohol.

  • How is oesophageal cancer diagnosed?

    Mainly by gastroscopy with a biopsy. The NHS says results should arrive within 2 weeks. Further tests such as CT or PET-CT scans find out how far it has spread.

  • How is oesophageal cancer treated?

    The NHS says it may include surgery, chemotherapy, radiotherapy, and targeted medicines and immunotherapy. The plan depends on the type, size, position, spread and your general health.

  • Is oesophageal cancer curable?

    The NHS says it is often treatable but can be difficult to treat. If found early and not spread, surgery may be possible. If it cannot be cured, treatment aims to limit the cancer and its symptoms and help you live longer.

  • How common is oesophageal cancer in the UK?

    Cancer Research UK says around 9,500 people are diagnosed each year in the UK. It is more common in men and older people, and very rare in people younger than 40.

  • Can heartburn turn into oesophageal cancer?

    Long-term severe acid reflux is a risk factor, according to the NHS. Most people with heartburn will not get cancer, but the NHS says to see a GP if you have heartburn most days that lasts for 3 weeks or more.

  • What is Barrett's oesophagus?

    The NHS says it is a condition where some cells in the oesophagus grow abnormally. It makes oesophageal cancer slightly more likely, but this is not common. It often has no symptoms.

  • What is the difference between squamous cell carcinoma and adenocarcinoma?

    They start in different cells. Cancer Research UK says squamous cell carcinomas tend to start in the upper and middle oesophagus, and adenocarcinomas in the lower part.

Where this comes from

Sources and checking.

This guide is for information, not medical advice.

Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.

Published 2026-10-11, next review 2027-10-11.