Skip to main content

Health condition

IgA nephropathy

IgA nephropathy is the world’s commonest glomerulonephritis - an immune condition where IgA antibody deposits inflame the kidney filters. Outcomes vary widely, and treatment is advancing quickly.

Why trust this guide

  • 01

    Editorial team

    Written by our editorial team from the UK sources listed on each page.

  • 02

    Sourced from guidance

    Checked against current NHS and UK specialist society guidance at the time of review.

  • 03

    Current for 2026

    Reviewed on 2026-09-27 with the next review scheduled for 2027-09-27.

Key facts

The essentials at a glance.

The symptoms to recognise, when to seek help, which specialist to see, and what treatment usually involves.

  • Typical presentations: visible blood in urine during a sore throat or cold, or silent blood and protein found on routine testing

  • Seek prompt review for cola-coloured urine, rising blood pressure, swelling, or a falling eGFR

  • Specialist: a consultant nephrologist usually leads assessment and treatment

  • Core care is blood pressure control with RAS blockade and SGLT2 inhibitors to cut protein leak; newer targeted therapies and immunosuppression are options for higher-risk disease

Understanding the condition

What it is and what happens next.

What causes it, how it is diagnosed, and the treatment routes available in the UK.

What it is and how it feels

In IgA nephropathy, abnormally formed IgA antibodies deposit in the glomeruli - the kidney’s filtering units - triggering inflammation and scarring. The classic story is visible haematuria within a day or two of a throat infection in a young adult. Severity ranges enormously: many people maintain normal function for life, while a proportion progress towards kidney failure over 10-20 years.

Diagnosis and treatment routes

Diagnosis requires a kidney biopsy, and risk is stratified by blood pressure, proteinuria and biopsy findings. Treatment has genuinely moved: beyond optimised supportive care, targeted-release budesonide and other new agents now address the disease process itself, making specialist follow-up - and clinical trial access - more valuable than ever. In many parts of the UK, routine NHS referrals for this kind of problem currently take 20-45+ weeks, whereas an initial appointment with a private consultant is typically available within around two weeks.

Seeing a specialist

Who to see, and how quickly you can be seen.

The specialist for this condition is usually a consultant nephrologist. Your GP can refer you on the NHS, or you can arrange a private consultation directly.

A quiet reminder

This guide is for information, not medical advice.

Your GP knows your history and can tell you which parts apply to you. If in doubt, see them - and seek urgent care for any of the emergency symptoms described above.

Frequently asked

Common questions about IgA nephropathy.

Quick, plain-English answers to what people ask us most.

  • Can you explain what IgA nephropathy is?

    IgA nephropathy describes a recognised clinical condition that a doctor can diagnose based on your symptoms, history, and any relevant tests. Its impact varies from person to person, so a proper assessment is the best way to understand your own case. Your GP or a specialist can talk you through what it means in practice.

  • What causes igA nephropathy?

    IgA nephropathy can develop for a number of reasons, and the exact cause often depends on individual factors such as underlying health, lifestyle, or in some cases injury. A clinician will usually take a history and may arrange tests to identify what's driving it in your case. Understanding the underlying cause helps guide the most appropriate treatment.

  • How would I know if I have igA nephropathy?

    The presentation of igA nephropathy differs between individuals, but it typically involves noticeable changes that prompt people to seek medical advice. Some people have mild symptoms that come and go, while others experience more persistent or severe effects. A clinical assessment is the most reliable way to confirm what's going on.

  • Is igA nephropathy serious or dangerous?

    Severity varies considerably, and while many cases are manageable with appropriate care, some can be more serious and need prompt attention. It's best not to self-diagnose severity, as similar symptoms can have very different underlying causes. A clinician can assess your specific situation and advise on the right next steps.

  • Does igA nephropathy run in families?

    There can be a hereditary element for some people, though many cases occur without any clear family link. If a close relative has been diagnosed with something similar, it's worth mentioning this to your doctor. This can help inform whether any additional monitoring or testing is worthwhile.

  • Is there a cure for igA nephropathy?

    Many cases can be effectively managed or improved with the right treatment, although whether it can be fully "cured" depends on the underlying cause. Early treatment generally gives the best chance of a good outcome. Your clinician can explain what's realistic to aim for in your specific case.

  • What treatment options are available for igA nephropathy?

    Depending on the cause and severity, treatment might involve medication, targeted therapy, monitoring, or in some cases a procedure. Most treatment plans start with the least invasive appropriate option and escalate only if needed. Your care team will personalise this based on your assessment and preferences.

  • How long does igA nephropathy last?

    Duration varies significantly depending on the cause, how promptly it's treated, and individual factors, so it's hard to give a single answer that applies to everyone. Some cases resolve within weeks with treatment, while others need longer-term management. Your clinician can give you a more specific timeframe once they understand your case fully.

  • When would I need to see a specialist for igA nephropathy?

    If first-line treatment isn't giving enough improvement, or if there are features that suggest a more complex underlying problem, a specialist referral is usually the next step. More invasive treatment is typically considered only after simpler options have been tried and haven't worked well enough. A specialist can assess whether this applies to your situation.

  • How quickly can I be seen for igA nephropathy?

    It's worth getting checked if things aren't improving, are getting worse, or are causing you ongoing worry or disruption. NHS routine referrals for this can take anywhere from around 20 to 45+ weeks depending on your local waiting list, while most private consultants can offer an initial appointment within about 2 weeks.