Women's health and mental wellbeing
Menopause mood changes: low mood, anxiety and irritability explained
Mood swings, low mood, anxiety and irritability are very common around perimenopause and menopause. They can be hormonal, linked to poor sleep or hot flushes, or related to life events, and they can also be depression that needs treatment in its own right. This guide explains what the NHS and NICE say about recognising and treating mood changes and when to get help urgently.
Last checked: 2026-10-10
Key facts
At a glance.
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Common
The NHS says it is common to have mood swings, low mood and anxiety around the time of the menopause and perimenopause.
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Can be depression
The NHS lists mood swings, low mood or depression together among symptoms of perimenopause and menopause, and says that if you have low mood, depression or anxiety caused by them you may be offered antidepressants.
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Sleep makes it worse
The NHS says problems with memory and concentration may feel worse with sleep problems and tiredness, and that poor sleep can make you feel irritable, stressed and anxious.
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CBT can help
The NHS says cognitive behavioural therapy is a type of talking therapy that can help with a low mood and feelings of anxiety, and with sleep problems.
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Early menopause deserves support
NICE says psychological support should be offered to people experiencing early menopause (between ages 40 and 44) who are distressed by their diagnosis or its consequences.
Mood changes at perimenopause and menopause
The NHS describes mood changes as one of the main groups of symptoms of perimenopause and menopause: you may have mood swings, low mood or depression, and you may also notice problems with your memory or concentration. It adds that symptoms can have a big impact on daily life, relationships, social life, family life and work.
Mood changes can begin during perimenopause, when periods are becoming irregular, and may continue after periods have stopped. The NHS says symptoms usually last 7 to 9 years, sometimes longer, and that they can change, for example hot flushes may improve and be replaced by other symptoms such as low mood and anxiety.
What is behind mood changes
The sources used here do not set out a single cause. They describe a network of linked symptoms. The NHS says sleep problems can make you feel irritable, stressed and anxious and may be worse if you also have night sweats. Hot flushes, palpitations and anxiety can themselves occur together, and the NHS notes that hot flushes can cause palpitations or anxiety.
Life circumstances also matter. Midlife can bring caring responsibilities, work pressures, changes in family life or bereavement, any of which can affect mood independently of the menopause. For that reason a GP will usually ask about the whole picture.
When it is more than a bad patch
The NHS describes depression as more than simply feeling unhappy or fed up for a few days: you feel persistently sad for weeks or months. Symptoms range from lasting feelings of unhappiness and hopelessness to losing interest in things you used to enjoy and feeling very tearful, and many people also have symptoms of anxiety. There can be physical symptoms such as constant tiredness, sleeping badly, having no appetite or sex drive and various aches and pains.
The NHS says it is important to seek help from a GP if you think you may be depressed and that it is best not to delay. Depression is a real illness, not a sign of weakness, and with the right treatment and support most people with depression can make a full recovery.
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Low mood or tearfulness lasting weeks rather than days.
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Losing interest or enjoyment in things you normally like.
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Persistent anxiety, panic or feeling on edge.
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Feeling hopeless, or that life is not worth living, which needs urgent help.
Self-help that is recommended
The NHS menopause advice for easing mood changes is to get as much rest as you can, exercise regularly and do relaxing activities. More generally it suggests keeping to regular sleep routines, eating a healthy balanced diet, trying yoga, tai chi or meditation, and talking to other people going through the same thing such as family, friends or colleagues. It advises not smoking and keeping within alcohol limits, as alcohol may affect symptoms.
The NHS depression overview adds that many people benefit from lifestyle changes such as getting more exercise, cutting down on alcohol, giving up smoking and eating healthily, and from reading a self-help book or joining a support group.
Treatments a GP may discuss
The NHS says the type of HRT offered depends on whether you still have periods and whether you have had a hysterectomy, and that oestrogen is the main type of HRT and can help manage symptoms. For low mood, depression or anxiety caused by perimenopause or menopause, the NHS says you may be offered antidepressants, and that CBT is a type of talking therapy that can help.
The NHS depression overview explains how treatment is chosen by severity: for mild depression a doctor may suggest watchful waiting, exercise and guided self-help, with talking therapies such as CBT; for moderate to severe depression a combination of talking therapy and antidepressants is often recommended; and severe depression may need referral to a specialist mental health team.
NICE's menopause guideline says menopause-specific CBT can be considered as an option for vasomotor symptoms and for sleep problems, alongside or instead of HRT, and that professionals should discuss the treatment options and the benefits and risks of each with you.
| Option | What it may help with | Notes |
|---|---|---|
| Lifestyle measures | Mood swings, low mood, sleep | Rest, regular exercise, relaxing activities, avoiding smoking and excess alcohol |
| CBT (talking therapy) | Low mood, anxiety, sleep problems, hot flushes | Available face to face, remotely, in groups or as self-help (NICE) |
| HRT (oestrogen, with progestogen if you have a womb) | Menopause symptoms generally | Type depends on whether you have periods or a hysterectomy |
| Antidepressants | Low mood, depression or anxiety caused by perimenopause or menopause | Offered where appropriate by a doctor |
When to get urgent help
Anyone who has thoughts of harming themselves or ending their life should get help straight away: contact a GP, call NHS 111, contact Samaritans, or call 999 or go to A&E if in immediate danger. These feelings can occur in depression at any age, and the NHS notes that severe depression can make you feel suicidal. They are treatable and asking for help is the right step.
The NHS also asks anyone with palpitations or a fast heartbeat to contact their GP, as these can occur in the menopause but should be checked.
NHS and private routes
GPs can assess mood, discuss HRT and refer to NHS Talking Therapies, which in England can be accessed through self-referral. NICE advises that healthcare professionals identify menopause as early as possible and discuss all the treatment options.
Some people choose private menopause clinics or private therapy for quicker access or longer appointments. The principles of treatment are the same, and it helps to keep your GP informed so that medicines are coordinated.
Frequently asked
Questions people ask.
Quick, plain-English answers to the questions we hear most.
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Are mood swings normal in the menopause?
Yes. The NHS says it is common to have mood swings, low mood and anxiety around the time of the menopause and perimenopause.
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How do I know if it is depression?
The NHS says depression involves feeling persistently sad for weeks or months, losing interest in things you enjoy and often anxiety and physical symptoms. See a GP if you think you may be depressed.
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Will HRT improve my mood?
The NHS says oestrogen HRT can help manage perimenopause and menopause symptoms. For low mood, depression or anxiety it also mentions antidepressants and CBT, so discuss the balance with a GP.
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What does CBT involve?
The NHS describes CBT as a talking therapy that can help with low mood and anxiety and with sleep problems. NICE says options include face-to-face or remote sessions, individual or group, and self-help.
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Can poor sleep make mood worse?
Yes. The NHS says sleep problems can make you feel irritable, stressed and anxious, and may be worse if you also have night sweats.
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What can I do myself?
The NHS suggests getting as much rest as you can, exercising regularly, doing relaxing activities, talking to others going through the same thing and avoiding smoking and excess alcohol.
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How long do these symptoms last?
The NHS says menopause and perimenopause symptoms usually last 7 to 9 years, sometimes longer, and can change over that time.
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Are antidepressants only for depression?
The NHS says antidepressants may be offered for low mood, depression or anxiety caused by perimenopause or menopause, and that an antidepressant may also be suggested for hot flushes if CBT does not help.
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What if I feel I cannot cope?
Speak to a GP promptly. The NHS says it is best not to delay seeking help for depression, and urgent help is available through NHS 111, Samaritans or 999 if you feel unsafe.
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Is early menopause different?
NICE says psychological support should be offered to people with early menopause between ages 40 and 44 who are distressed by their diagnosis or its consequences, and referral to psychology services if needed.
Where this comes from
Sources and checking.
This guide is for information, not medical advice.
Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.
Published 2026-10-10, next review 2027-10-10.
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NHS: Symptoms of menopause and perimenopause, https://www.nhs.uk/conditions/menopause/symptoms/ , retrieved October 2026
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NHS: Treatment for menopause and perimenopause, https://www.nhs.uk/conditions/menopause/treatment/ , retrieved October 2026
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NHS: Things you can do to help menopause and perimenopause symptoms, https://www.nhs.uk/conditions/menopause/things-you-can-do/ , retrieved October 2026
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NHS: Depression in adults overview, https://www.nhs.uk/mental-health/conditions/depression-in-adults/overview/ , retrieved October 2026
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NICE: Menopause: identification and management (NG23), recommendations, https://www.nice.org.uk/guidance/ng23/chapter/Recommendations , retrieved October 2026
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