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Multi-Organ Failure

Failure of multiple organ systems; poor prognosis; supportive care for each system.

Key Information

  • Medical professional consultation recommended
  • Appropriate evaluation important
  • Multiple management approaches available
  • Specialized care may be beneficial

About Multi-Organ Failure

Failure of multiple organ systems; poor prognosis; supportive care for each system.

For comprehensive information about diagnosis, treatment options, and management, consult with your healthcare provider or a relevant specialist.

Frequently asked

Common questions about Multi-Organ Failure.

Quick, plain-English answers to what people ask us most.

  • What is multi-organ failure?

    Multi-organ failure is a life-threatening condition in which two or more organ systems, such as the kidneys, lungs, liver and heart, fail to function adequately, usually as a result of severe illness such as sepsis, major trauma or a critical surgical complication.

  • What causes multi-organ failure?

    It's most commonly caused by severe sepsis, major trauma, extensive burns, or prolonged shock from any cause, all of which trigger widespread inflammation and impaired blood flow that progressively damages multiple organs.

  • What are the signs of multi-organ failure?

    Signs vary by which organs are affected but can include confusion, very low or no urine output, breathing difficulty requiring ventilator support, abnormal liver function, and dangerously low blood pressure requiring medication to maintain.

  • Is multi-organ failure dangerous?

    Yes, multi-organ failure is a medical emergency with a high risk of death, and outcomes depend heavily on how many organs are involved, the underlying cause, and how quickly intensive treatment is started.

  • How is multi-organ failure treated?

    Treatment takes place in an intensive care unit and involves supporting each failing organ, such as ventilator support for the lungs, dialysis for the kidneys, and medication to support blood pressure, while treating the underlying cause such as infection.

  • Can someone recover fully from multi-organ failure?

    Recovery is possible, particularly if the underlying cause is treated promptly and effectively, though some people experience lasting organ impairment, and recovery, including rehabilitation, can take many months after a severe episode.

  • When should someone seek emergency care for possible multi-organ failure?

    This is a medical emergency requiring immediate hospital care; anyone showing signs of severe illness such as confusion, very low urine output or difficulty breathing alongside a serious infection or injury should go to A&E or call 999 without delay.