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Cancer treatment side effects

Radiation burn: radiotherapy skin reactions, care and recovery

A radiation burn is the skin reaction that can develop in the area treated with radiotherapy. It ranges from mild pinkness and dryness to soreness, blistering and peeling, and it usually settles after treatment ends. This guide explains when it starts, what makes it worse, how to look after the skin and when to contact your treatment team.

Last checked: 2026-10-10

Key facts

At a glance.

  • A common side effect

    The NHS says radiotherapy can make your skin sore, change colour, or become dry and itchy, and that sometimes it can blister and peel.

  • Timing

    The NHS says skin changes tend to start 1 to 2 weeks after treatment begins. A Gloucestershire Hospitals leaflet says a reaction usually begins about 10 days after starting and continues after treatment is completed.

  • Usually settles

    The NHS says skin problems usually settle within 2 to 4 weeks of treatment finishing, though the skin can stay slightly darker or lighter than before.

  • Skin folds and other factors

    The Gloucestershire leaflet says skin folds, treatment to the head and neck, chemotherapy given alongside radiotherapy, smoking, being overweight, heart disease and diabetes can make a reaction worse.

  • Self-care helps comfort

    The leaflet says it may not be possible to stop a skin reaction, but following skin care advice may help you feel more comfortable.

  • Tell your team

    The NHS advises telling your care team if you notice any soreness or changes to your skin, and to stop using products on the skin if it breaks.

What a radiation burn is

Radiotherapy uses high-energy rays to treat cancer, and the beams pass through the skin on their way to the area being treated. Healthy skin cells in the treated area can be affected too. The result is a skin reaction that people often call a radiation burn. It is not a burn in the sense of a heat injury, but it can look and feel like sunburn.

The NHS lists skin soreness as one of the side effects of radiotherapy and explains that side effects vary from person to person and depend on factors such as the part of the body being treated and the type of radiotherapy. It adds that many side effects can be treated or prevented and most go away after treatment stops, and that in some cases side effects only develop months or even years after treatment starts.

The Gloucestershire Hospitals leaflet describes a skin reaction as something you may develop during radiotherapy and for a while afterwards, in the area being treated. It is local: it affects the skin in the treated area rather than the whole body.

Most people have some degree of skin change. Many have only mild changes that are managed with moisturiser and gentle care, while a smaller number have more troublesome blistering or peeling that needs dressings and pain relief.

What it looks and feels like

The Gloucestershire leaflet describes the skin in the treated area gradually becoming pinker or darker, depending on skin tone, feeling dry or tight and sore, or developing a rash and itching. The NHS describes the skin becoming sore, changing colour (red, lighter or darker than your usual skin tone), or dry and itchy, and sometimes blistering and peeling.

Both sources describe the colour change in relation to your usual skin tone, so it may look darker or lighter rather than red. Soreness, tightness and itching are also part of the picture.

  • Pinker, redder or darker skin in the treated area.

  • Dryness, tightness or soreness.

  • Itching or a rash.

  • In more severe reactions, blisters or peeling skin, especially in skin folds.

  • Skin that is slightly darker or lighter than before once it has healed.

When it starts and how long it lasts

The sources give slightly different timings, which reflects the fact that reactions vary. The NHS says changes tend to start 1 to 2 weeks after treatment begins. The Gloucestershire leaflet says a reaction usually begins about 10 days after starting treatment, may appear at any time and continues after radiotherapy is completed.

The skin may get worse before it gets better. The leaflet says your skin reaction may worsen for 7 to 14 days after finishing radiotherapy, then gradually improve, and that most patients find their skin has healed by about a month after treatment finishes, although if the skin has broken, healing may take longer. The NHS says skin problems usually settle within 2 to 4 weeks of treatment finishing, though sometimes your skin might stay slightly darker or lighter than before.

What can make it worse

The Gloucestershire leaflet lists several things that can make a skin reaction worse. Having treatment to areas with skin folds, such as the groin, breast, anal or rectal area or armpit, can worsen it because these areas can be warm, moist and rub together, and the skin may develop blisters or peel. Treatment to the head and neck can result in a more severe reaction because the skin in this area receives a higher dose due to the position of the tumour.

Systemic anti-cancer treatments such as chemotherapy given alongside radiotherapy can increase the sensitivity of the treated area. Smoking will make a skin reaction worse, and a reaction is also more likely if you are overweight or have other conditions such as heart disease or diabetes. The leaflet advises asking your treatment team for help to stop smoking.

Looking after the skin

The NHS and the Gloucestershire leaflet give broadly similar skin care advice, and your own radiotherapy team may give you more specific instructions that take priority. The advice applies to the skin in the treated area.

Skin care advice described by the NHS and Gloucestershire Hospitals
TopicWhat the sources advise
WashingWash gently with your usual soap and water and pat dry rather than rubbing
MoisturiserUse your usual moisturiser or start one; the leaflet suggests applying it thinly twice a day and says no moisturiser has been shown to be better than another, though it suggests choosing one free from sodium lauryl sulphate
ClothingWear loose-fitting clothes made from natural fibres such as cotton; avoid tight bands, ties or straps on the sore area
Shaving and hair removalAvoid shaving if possible; do not use wax or hair-removal creams
Heat and coldAvoid heat or cold packs and extremes of temperature on the area
SunThe NHS advises high-factor sunscreen (SPF 50 or above) and continuing for at least a year after treatment; the leaflet suggests a minimum SPF 30 with UVA protection, a brimmed hat and cover-up clothing for at least a year
Tape and productsAvoid sticky tape on the area, and stop using products on the skin if it breaks
SwimmingCheck with your care team; chlorine can sometimes make the skin worse. The leaflet says you may swim if the skin is not broken, then shower and moisturise

When to contact your team

The NHS advises telling your care team if you notice any soreness or changes to your skin, and to stop using any products on your skin if it breaks. The Gloucestershire leaflet explains that if the skin blisters or peels, the team will be able to help with dressings and pain relief.

Contact your radiotherapy team or review radiographer straight away if the skin becomes very sore, breaks open, weeps, smells or looks infected. The Gloucestershire leaflet notes that you can contact the team after the end of radiotherapy for advice by telephone or in a face-to-face appointment, and that contact details are given at the end of the course.

Always ask your team before applying creams or dressings that were not recommended to you, because some products can irritate the skin or affect treatment.

Long-term care of treated skin

Treated skin stays more sensitive to the sun for a long time. The NHS recommends continuing sunscreen for at least a year after treatment ends, and the leaflet advises being careful in the sun for at least a year after finishing.

Treated skin may stay slightly darker or lighter, as the NHS notes. The NHS also says that radiotherapy side effects can occasionally appear months or years after treatment, so tell your GP or cancer team about any new skin changes in a previously treated area.

Radiotherapy in the NHS is delivered through hospital cancer centres. Skin care advice may vary between centres, so keep to the instructions you were given at your own centre.

Frequently asked

Questions people ask.

Quick, plain-English answers to the questions we hear most.

  • Is a radiation burn the same as sunburn?

    It can look and feel similar, with redness, soreness and peeling, but it is caused by radiotherapy rather than sunlight and is confined to the treated area. The NHS describes it as sore, colour-changed, dry or itchy skin that may blister and peel.

  • When does it start?

    The NHS says skin changes tend to start 1 to 2 weeks after treatment begins. The Gloucestershire leaflet says about 10 days after starting.

  • When will it heal?

    The NHS says skin problems usually settle within 2 to 4 weeks of treatment finishing. The Gloucestershire leaflet says most people find their skin has healed by about a month after treatment finishes.

  • Can I stop it happening?

    The Gloucestershire leaflet says it may not be possible to stop a skin reaction, but following skin care advice may help you feel more comfortable.

  • Which moisturiser should I use?

    The leaflet says there is no evidence that any one moisturiser is better than another, so you may use your usual product, ideally free from sodium lauryl sulphate if buying a new one. It does not recommend a specific product.

  • Can I shave the area?

    The NHS advises avoiding shaving the area if possible and not using laser, wax or hair-removal creams.

  • Can I swim?

    The NHS advises checking with your care team because chlorine can sometimes make the skin worse. The Gloucestershire leaflet says you may swim if the skin is not broken and should shower and moisturise afterwards.

  • What if the skin breaks?

    Stop using products on it and contact your team. The NHS advises stopping products if the skin breaks, and the leaflet says the team can help with dressings and pain relief.

  • How long should I protect the area from the sun?

    The NHS advises using high-factor sunscreen for at least a year after treatment ends, and the Gloucestershire leaflet says to be careful in the sun for at least a year.

Where this comes from

Sources and checking.

This guide is for information, not medical advice.

Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.

Published 2026-10-10, next review 2027-10-10.