Patient guide
NICE criteria for weight-loss medicines, explained plainly
NICE sets out who the NHS should offer weight-loss medicines to. The criteria combine body mass index with other health conditions and, in some cases, referral to a specialist service. This guide translates them into everyday language and explains why they exist.
Last checked: 2026-10-03
Key facts
At a glance.
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Tirzepatide
NICE guidance TA1026 recommends tirzepatide for adults with an initial BMI of at least 35 and at least one weight-related condition, as part of a weight-management programme.
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Semaglutide
NICE guidance TA875 recommends semaglutide for adults with at least one weight-related condition and an initial BMI of 35 or more, or 30 to 34.9 where criteria for specialist referral are met. It is intended for use in specialist services.
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Lifestyle support
Both appraisals assume the medicine is used alongside support with diet, activity and behaviour, not instead of it.
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NHS is not private
NICE criteria apply to NHS funding. Private prescribers are not bound by them but must still justify treatment clinically.
What the criteria are really measuring
Body mass index is a rough screening tool, calculated from height and weight. NICE uses it with other information because on its own it does not describe health. The criteria aim to direct limited NHS resources to people who are most likely to gain medical benefit, such as a lower risk of diabetes, heart disease or joint problems.
This is why people sometimes find that they sit just below the threshold and cannot access NHS treatment, while someone else with a slightly higher number can. The line is a pragmatic funding rule, not a statement about who deserves care.
Adjusting for ethnicity
NICE obesity guidance recognises that health risks from excess weight appear at lower BMI levels in people of South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean family background. Clinicians are advised to use lower BMI thresholds for these groups when deciding who to assess or refer. If you belong to one of these groups and are told you do not qualify, it is reasonable to ask whether adjusted thresholds were applied.
Specialist services and time limits
The semaglutide appraisal places treatment in specialist weight-management services, where people are usually supported for a limited period rather than indefinitely. The tirzepatide appraisal allows prescribing in primary care or specialist services depending on local arrangements. Local commissioners decide how and when these pathways open, which explains why access differs between areas.
What happens at review
On the NHS, continuing treatment generally depends on showing adequate response within a defined period. If the response is not enough, the recommendation is to stop. Services also review side effects and whether the person remains engaged with the supporting programme. Ask at the start what the review points are and what counts as a satisfactory response.
If you do not meet the criteria
Not meeting NICE criteria does not mean you have no options. You can ask your GP about structured behavioural programmes, dietetic support, treatment for conditions such as sleep apnoea or high blood pressure, and the older weight-management medicine orlistat. Some people consider private assessment. A private prescriber who offers a medicine at a BMI below the licensed threshold is making an off-licence decision and should explain the reasoning and the limits of the evidence.
Frequently asked
Questions people ask.
Quick, plain-English answers to the questions we hear most.
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Do I need to have diabetes to qualify?
No. Qualification depends on BMI and the presence of at least one weight-related condition, which could be high blood pressure or sleep apnoea rather than diabetes.
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Does my BMI at the start or now count?
NICE refers to the initial BMI, meaning your BMI before you began a programme or treatment, so earlier weight loss does not automatically remove eligibility.
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Why does the NHS require a weight-management programme as well?
Trial evidence on these medicines was gathered alongside lifestyle support, and the supporting programme helps with nutrition, activity and adherence.
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Are the criteria the same in Scotland, Wales and Northern Ireland?
NICE guidance applies in England. Scotland, Wales and Northern Ireland have their own bodies and decisions, so confirm local policy.
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Can I be referred if my BMI is below 35?
For semaglutide, a BMI from 30 to 34.9 can qualify if you meet specialist-referral criteria. Lower thresholds may apply to some ethnic groups.
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What if my GP says the local service is not open yet?
Phased rollout means some areas start later. Ask your GP practice or integrated care board when your area expects to offer it.
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Does pregnancy planning affect eligibility?
These medicines are not recommended in pregnancy, so plans for pregnancy need to be discussed before treatment starts.
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Is BMI the only measurement used?
Services often consider waist measurement and body composition where relevant, but BMI remains the main funding threshold.
Where this comes from
Sources and checking.
This guide is for information, not medical advice.
Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.
Published 2026-10-03, next review 2027-10-03.
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NICE guideline NG246, Overweight and obesity management (nice.org.uk)
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NICE technology appraisal TA1026, Tirzepatide for managing overweight and obesity (nice.org.uk)
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NICE technology appraisal TA875, Semaglutide for managing overweight and obesity (nice.org.uk)
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NHS website, Obesity and weight-loss medicines pages (nhs.uk)