Patient guide
Sleeping tablets in the UK: short-term use, risks and alternatives
Prescription sleeping tablets can give short-term relief but are not intended for long-term use. They can cause dependence, next-day drowsiness and falls. Melatonin has narrower licensed uses. This guide explains how these medicines are prescribed, how to stop them safely and which alternatives have stronger evidence.
Last checked: 2026-10-03
Key facts
At a glance.
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Short courses
Guidance advises using hypnotic medicines at the lowest effective dose for the shortest time, typically days to a couple of weeks.
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Dependence
Tolerance and dependence can develop quickly with regular use.
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Melatonin
Melatonin is prescription-only in the UK, with licensed uses that are limited to particular groups.
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Better long-term option
CBT for insomnia is recommended as first-line for long-term insomnia.
Types of medicine
Z-drugs such as zopiclone and zolpidem, and benzodiazepines such as temazepam, act on brain receptors to promote sleep. Some antihistamines sold over the counter cause drowsiness but lose effect and can cause next-day grogginess and confusion in older people. Certain antidepressants are sometimes used at low doses for sleep, usually when mood is also affected. Newer medicines that block orexin signalling are available for chronic insomnia in specific circumstances.
Why prescribers are cautious
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Tolerance: the effect diminishes with regular use.
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Dependence and withdrawal, including rebound insomnia and anxiety.
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Next-day drowsiness, impaired concentration and driving risk.
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Falls and confusion, especially in older adults.
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Interactions with alcohol and other sedatives.
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Possible complex sleep behaviours such as sleepwalking with Z-drugs.
Melatonin in the UK
Melatonin is a hormone that regulates the sleep-wake cycle. In the UK it is prescription-only, with a licensed modified-release product for short-term treatment of insomnia in people aged 55 and over, and other formulations used for specific childhood neurodevelopmental sleep problems. Products sold online or as supplements elsewhere vary in strength and are not regulated in the same way here. Do not import or buy unregulated melatonin without advice.
Driving and safety
Some sleeping medicines impair driving the next day. It is an offence to drive while impaired by any drug, and some medicines are covered by specific drug-driving limits, with a medical defence if taken as prescribed and not impaired. Avoid driving if you feel drowsy. Do not combine with alcohol. Store tablets safely, away from children.
Stopping safely
If you have taken sleeping tablets regularly for weeks or months, do not stop suddenly. A prescriber can supervise gradual dose reduction, often over weeks to months, and may combine it with CBT for insomnia. Expect some temporary sleep disturbance. Withdrawal symptoms such as anxiety, tremor, sweating or seizures need medical attention. Support is available through GPs and addiction services.
Alternatives with better evidence
CBT for insomnia, sleep scheduling, relaxation techniques, regular wake times, daylight exposure, daytime activity, limiting caffeine and alcohol and treating underlying conditions such as sleep apnoea, restless legs, pain, menopause symptoms or depression help sleep more durably. If you take medicines that disturb sleep, such as some stimulants, steroids or beta-blockers, ask your clinician about timing or alternatives.
Questions to ask before starting
Ask why a sleeping tablet is being suggested, how long you should take it and what the plan is for stopping. Ask about side effects, driving and alcohol, and whether there are alternatives that could be started alongside it, such as CBT for insomnia. Ask what to do if it does not help or if you feel unusually drowsy. If you already take other sedating medicines, mention them. If you are older or have breathing problems, ask specifically about falls and about the effect on breathing during sleep.
Frequently asked
Questions people ask.
Quick, plain-English answers to the questions we hear most.
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How long can I take sleeping tablets?
Usually for short courses only. Your prescriber will advise on duration.
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Are they addictive?
Dependence can develop with regular use, which is why use is limited.
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Can I buy melatonin over the counter?
Not in the UK as a licensed medicine. It requires a prescription.
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Is it safe with alcohol?
No. Alcohol increases sedation and risks.
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What if I cannot sleep without them?
Speak to your GP about gradual reduction and CBT for insomnia.
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Do herbal remedies work?
Evidence is limited. Valerian and others may help some people slightly, but quality varies.
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Can older people take them?
With particular caution because of falls and confusion. Alternatives are preferred.
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Do they work for sleep apnoea?
Sedatives can worsen sleep apnoea, so tell your clinician if you snore or stop breathing in sleep.
Where this comes from
Sources and checking.
This guide is for information, not medical advice.
Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.
Published 2026-10-03, next review 2027-10-03.
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NHS website, Sleep apnoea and Insomnia pages (nhs.uk)
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MHRA drug safety updates and Yellow Card scheme information (gov.uk/mhra)
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General Medical Council, Good practice in prescribing and managing medicines and devices (gmc-uk.org)
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DVLA, Assessing fitness to drive: a guide for medical professionals (gov.uk/dvla)