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Fentanyl + Ketoconazole

Major: Respiratory depression; ketoconazole increases fentanyl. Use alternative analgesic or reduce fentanyl dose.

Interaction Details

  • Severity classification
  • Mechanism of interaction
  • Clinical management
  • Alternative options

Clinical Significance

Major: Respiratory depression; ketoconazole increases fentanyl. Use alternative analgesic or reduce fentanyl dose.

Always consult with your pharmacist or healthcare provider before starting any new medications to check for potential interactions.