Midazolam + Fluconazole
Major: Prolonged sedation; fluconazole inhibits CYP3A4. Use lower midazolam doses; consider alternative benzodiazepine.
Interaction Details
- Severity classification
- Mechanism of interaction
- Clinical management
- Alternative options
Clinical Significance
Major: Prolonged sedation; fluconazole inhibits CYP3A4. Use lower midazolam doses; consider alternative benzodiazepine.
Always consult with your pharmacist or healthcare provider before starting any new medications to check for potential interactions.