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Warfarin + Amiodarone

Major: Markedly increased INR; amiodarone increases warfarin levels. Reduce warfarin 30-50%; monitor INR closely.

Interaction Details

  • Severity classification
  • Mechanism of interaction
  • Clinical management
  • Alternative options

Clinical Significance

Major: Markedly increased INR; amiodarone increases warfarin levels. Reduce warfarin 30-50%; monitor INR closely.

Always consult with your pharmacist or healthcare provider before starting any new medications to check for potential interactions.