Skip to main content

Medicine guide

Diclofenac gel: using a topical NSAID on sore joints and muscles

Diclofenac gel is a topical anti-inflammatory applied to the skin over a painful joint or muscle. Because far less reaches the bloodstream than with tablets, it carries fewer systemic risks, but it is not risk-free and has its own skin, sun and fire cautions. This guide pulls together the NHS advice and the UK product information for a widely used 1.16% gel.

Last checked: 2026-10-03

Key facts

At a glance.

  • What it treats

    Local pain and inflammation from trauma of tendons, ligaments, muscles and joints (sprains, strains, bruises), localised soft tissue rheumatism, and osteoarthritis of superficial joints such as the knee.

  • Amount and frequency

    The product information gives 2 to 4g (a circular mass about 2.0 to 2.5cm across) 3 to 4 times a day for adults and children aged 14 and over; the NHS says no more than 4 times in 24 hours.

  • Review points

    Review after 14 days for soft tissue injuries and after 4 weeks for osteoarthritis.

  • Skin only

    For use on intact skin only, not on wounds, and keep away from eyes and mucous membranes.

  • Fire warning

    Do not smoke or go near naked flames; fabric that has been in contact with the product burns more easily.

  • Pregnancy

    Contraindicated in the third trimester; the NHS notes diclofenac is not usually recommended in pregnancy.

What diclofenac gel is for

Diclofenac is an NSAID, and the NHS says that when you apply it to the skin as gel, plasters or patches it works in the same way as in tablet form, but only on the area you have treated. The UK product information for Voltarol Emulgel lists local symptomatic relief of pain and inflammation in trauma of the tendons, ligaments, muscles and joints, such as sprains, strains and bruises, in localised soft tissue rheumatism, and in osteoarthritis of superficial joints such as the knee.

The NHS notes that gels and plasters can be bought from pharmacies for joint pain, while tablets are prescription-only, and that diclofenac does not work for some types of pain, such as nerve pain.

How to apply it

Gently squeeze a small amount from the tube or dispenser and rub it slowly into the painful or swollen area. The NHS describes an amount about the size of a cherry or walnut, 2 to 4 grams, depending on the area, used 2 to 4 times a day according to strength, with at least 4 hours between applications if using it 3 or 4 times, and never more than 4 times in any 24 hours.

Wipe the hands with a paper towel and wash them afterwards unless the hands are the area being treated; wipe off excess gel with a paper towel and dispose of it in household waste. Let the gel dry for a few minutes before applying a bandage. It can be used with non-occlusive bandages but not under an airtight dressing. Adults and children aged 14 and over use the same adult range, and it is contraindicated in children under 14.

How long it takes and how long to use it

The NHS says gel typically takes 1 to 2 days to work, and for arthritis you may need to use it for up to 7 days on the painful joint to feel the full effect. When you stop, the effects wear off after 1 or 2 days.

The product information recommends reviewing treatment after 14 days for injuries and soft tissue rheumatism, and after 4 weeks for osteoarthritis. If pain persists beyond those points, the next step is a review rather than more gel.

Side effects and skin care

Local effects are the usual ones: rash, eczema, redness, dermatitis and itching are common, with blistering dermatitis rare and photosensitivity reactions very rare. The NHS suggests moisturising dry or irritated skin, using the gel less often (once a day, or every other day) or pausing for a few days, and an over-the-counter antihistamine for itching after checking with a pharmacist. Stop using the gel if a rash develops after application.

Protect the treated area from strong sunlight and use sun cream (SPF 30 or above), and avoid sunlamps and sunbeds. Rarely, systemic NSAID effects can occur if a lot is used on a large area of skin, and bronchospasm can be precipitated in people with asthma. If the gel is swallowed, call NHS 111.

Who should not use it

The product information lists contraindications of asthma, angioedema, urticaria or acute rhinitis precipitated by aspirin or other NSAIDs, hypersensitivity to diclofenac or any ingredient, the third trimester of pregnancy, and use in children under 14. Using systemic NSAIDs at the same time warrants caution, because untoward effects could increase. Some gut bleeding has been reported in isolated cases in people with a significant history.

The NHS says to tell your doctor or pharmacist about any previous reactions to aspirin or NSAIDs, stomach ulcers, heart, kidney or liver problems, and asthma.

Pregnancy, breastfeeding and other medicines

Diclofenac is not usually recommended in pregnancy, and the NHS says paracetamol is generally the first-choice painkiller. The product information states the third trimester is a contraindication because NSAIDs can affect the baby's heart, lungs and kidneys and the mother's labour. It passes into breast milk in small amounts, and the NHS says you can use diclofenac while breastfeeding, taking care that your baby does not touch treated skin and washing your hands before picking the baby up.

Because systemic absorption from topical use is very low, interactions are unlikely, but tell a pharmacist about regular NSAIDs, anticoagulants or other medicines you use.

Frequently asked

Questions people ask.

Quick, plain-English answers to the questions we hear most.

  • How often can I use diclofenac gel?

    The NHS says you will usually use it 2 to 4 times a day depending on strength, and not more than 4 times in any 24-hour period, leaving at least 4 hours between applications if using it 3 or 4 times.

  • How much gel is one application?

    About a cherry- or walnut-sized amount, 2 to 4 grams, depending on the size of the area being treated, according to the NHS.

  • How long before it works?

    The NHS says gel usually takes 1 to 2 days to work, and for arthritis up to 7 days on the painful joint for the full effect.

  • When should treatment be reviewed?

    The product information recommends reviewing after 14 days for injuries and soft tissue rheumatism and after 4 weeks for osteoarthritis.

  • Can I put a bandage over it?

    Yes, a non-occlusive bandage after the gel has dried for a few minutes. It should not be used with an airtight occlusive dressing.

  • Why must I avoid naked flames?

    The product information says fabric that has been in contact with the product burns more easily and is a serious fire hazard, so do not smoke or go near naked flames.

  • Can I use it on broken skin?

    No. It should only be applied to intact, non-diseased skin and not to wounds or open injuries, and kept away from eyes and mucous membranes.

  • Is it safe in pregnancy?

    The third trimester is a contraindication, and diclofenac is not usually recommended in pregnancy. Speak to a pharmacist, midwife or doctor before using it.

  • Can I use it while breastfeeding?

    The NHS says you can, because only tiny amounts reach breast milk. Make sure your baby does not touch treated skin and wash your hands first.

Where this comes from

Sources and checking.

This guide is for information, not medical advice.

Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.

Published 2026-10-03, next review 2027-10-03.