Medicine guide
Escitalopram: uses, side effects and cautions
Escitalopram is an SSRI with one of the wider lists of uses in the NHS guidance: depression, OCD and three anxiety disorders. It is available only on prescription, and the UK brand listed by the NHS is Cipralex.
Last checked: 2026-10-03
Key facts
At a glance.
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Five uses
Depression, obsessive compulsive disorder, generalised anxiety disorder, social anxiety disorder and panic disorder.
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Brand
Cipralex is the brand listed by the NHS. It is prescription-only.
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Three forms
Tablets swallowed whole, orodispersible tablets that dissolve on the tongue, and liquid drops.
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Usual schedule
Once a day, with or without food.
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Duration
For depression, the NHS says you will probably need to keep taking it for 6 months or more.
What escitalopram is used to treat
The NHS lists five conditions. Depression and OCD are two; the other three are generalised anxiety disorder, social anxiety disorder and panic disorder. This breadth means a prescriber may choose it when a person has depression alongside anxiety.
It is an SSRI, so it increases serotonin levels in the brain.
Choosing a form
Escitalopram comes as ordinary tablets, as orodispersible tablets and as liquid drops. Tablets are swallowed whole. Orodispersible tablets dissolve on the tongue, which can help if swallowing pills is difficult. Drops are an alternative for those who prefer a liquid.
It is usually taken once a day. Eating or not eating makes no difference.
How soon it helps and how long it lasts
The NHS says it can take several weeks until your symptoms start to improve. For depression, plan on taking it for six months or more, because stopping early can allow symptoms to return.
If you miss a dose, take it as soon as you remember unless the next dose is soon, and never take two together. The NHS describes an extra dose as dangerous and says to call NHS 111 if that happens.
Side effects and when to get help
Most side effects ease within a couple of weeks. The NHS says some can last longer; tell a pharmacist or doctor if they trouble you.
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Common: headaches, nausea or vomiting, sweating, diarrhoea or constipation, joint or muscle pain, dizziness, sleepiness, anxiety, restlessness, weight or appetite changes, sleep problems and reduced sex drive.
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Serious, via NHS 111: anaphylaxis, serotonin syndrome, an irregular heartbeat called torsades de pointes (sometimes with fainting), internal bleeding, or thoughts of suicide or self-harm.
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If told to go to A&E, call an ambulance rather than driving yourself.
Heart rhythm and other cautions
Heart rhythm problems, bleeding disorders, kidney or liver issues, diabetes, epilepsy, heart disease, glaucoma and previous mania are all on the NHS list of points to raise before starting. A past serious reaction to an antidepressant matters too.
The NHS names MAOIs, heart rhythm medicines, warfarin, aspirin and ibuprofen, antihistamines, ulcer medicines and St John's wort as medicines or supplements that can clash with it.
Pregnancy, breastfeeding and alcohol
The NHS says escitalopram can be used in pregnancy if needed at the lowest effective dose, with a hospital birth recommended. It is sometimes used while breastfeeding, but you should discuss that with your doctor first.
Alcohol increases side effects such as drowsiness, so the NHS says it is best not to drink.
Stopping escitalopram
Do not stop suddenly. The dose is reduced gradually over several weeks or months so the body can adjust. Suspected side effects can be reported through the MHRA Yellow Card scheme.
Frequently asked
Questions people ask.
Quick, plain-English answers to the questions we hear most.
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Which conditions can escitalopram treat?
The NHS lists depression, OCD, generalised anxiety disorder, social anxiety disorder and panic disorder.
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What is the brand name of escitalopram?
The NHS lists Cipralex.
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Can I take it if I cannot swallow tablets?
Orodispersible tablets that dissolve on the tongue and liquid drops are available, so ask your prescriber about a different form.
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How long does escitalopram take to work?
The NHS says it can take several weeks before symptoms start to improve.
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How long should I stay on it for depression?
The NHS says you will probably need to keep taking it for 6 months or more.
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Is escitalopram bad for the heart?
The NHS lists irregular heartbeat (torsades de pointes) as a serious but uncommon effect and names heart rhythm problems among the cautions, so tell your prescriber about any heart history.
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Can I drink alcohol on escitalopram?
It is best not to, because alcohol can increase side effects such as drowsiness.
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Is it safe in pregnancy or breastfeeding?
The NHS says it can be used in pregnancy if needed, and is sometimes used while breastfeeding. Discuss both with your doctor rather than stopping alone.
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What if I take an extra dose by mistake?
The NHS says taking an extra dose can be dangerous. Call NHS 111 straight away.
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What happens if I stop suddenly?
Withdrawal symptoms may occur. The dose should be lowered gradually over several weeks or months with your prescriber.
Where this comes from
Sources and checking.
This guide is for information, not medical advice.
Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.
Published 2026-10-03, next review 2027-10-03.
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NHS medicines information: escitalopram - patient information from the NHS website, https://www.nhs.uk/medicines/escitalopram/, retrieved October 2026
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NHS medicines information: escitalopram side effects - patient information from the NHS website, https://www.nhs.uk/medicines/escitalopram/side-effects-of-escitalopram/, retrieved October 2026
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NHS medicines information: escitalopram common questions - patient information from the NHS website, https://www.nhs.uk/medicines/escitalopram/common-questions-about-escitalopram/, retrieved October 2026
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MHRA Yellow Card scheme - the UK system for reporting suspected side effects, https://yellowcard.mhra.gov.uk, retrieved October 2026
Related guides
Keep reading.
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Generalised anxiety disorder
Persistent worry and the options for treating it.
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Social anxiety disorder
Understanding fear of social situations.
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Panic disorder
How panic disorder is recognised and treated.
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Depression
Symptoms, causes and treatment routes for depression.
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