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Medicine guide

The progestogen-only pill (mini pill): timing windows, side effects and who can take it

The progestogen-only pill, or mini pill, is a hormonal contraceptive that contains progestogen and no oestrogen. It stops the ovaries releasing an egg each month and is over 99% effective when used correctly. The detail that matters most is timing, because the window for a late pill differs by pill type. This guide sets out what the NHS says.

Last checked: 2026-10-03

Key facts

At a glance.

  • Contains

    Progestogen only, with no oestrogen.

  • Effectiveness

    Over 99% with perfect use; the NHS gives 91% with typical use, about 9 pregnancies per 100 women a year.

  • Late-pill window

    Within 3 hours for traditional pills, within 12 hours for desogestrel, and within 24 hours for drospirenone.

  • Packs

    28 pills with no break between packs.

  • Periods

    May become lighter, more frequent or stop, with spotting between cycles possible.

  • Fertility

    Usually takes about 1 month after stopping for the chance of pregnancy to return to normal.

What the mini pill is

The progestogen-only pill is a hormonal contraceptive containing progestogen, which mimics the effects of progesterone. It prevents pregnancy by stopping the ovaries releasing an egg each month. Types mentioned by the NHS are the traditional pill, desogestrel and drospirenone.

Because it contains no oestrogen, it can suit people who cannot tolerate it, as well as those who have recently given birth or who are breastfeeding. It may also help with painful or heavy periods and endometriosis.

Taking it at the same time, and what counts as late

Take one pill at around the same time every day, with no break between 28-pill packs. How late is too late depends on the pill type.

Late-pill windows described by the NHS
Pill typePill still covered if taken within
Traditional3 hours of the usual time
Desogestrel12 hours of the usual time
Drospirenone24 hours of the usual time

When protection begins

Starting on days 1 to 5 of your cycle gives immediate protection with traditional and desogestrel pills. For drospirenone only day 1 gives immediate protection. If you start later, use condoms for 2 days with traditional or desogestrel pills, or 7 days with drospirenone.

After a birth, starting within 20 days gives immediate protection; from 21 days, extra contraception is needed for 2 to 7 days depending on the type.

Who cannot take it

The NHS says the pill is not suitable if you have ever had a heart or blood vessel condition (cardiovascular disease), a stroke, a liver condition such as cirrhosis, breast cancer or a kidney condition. Talk to a doctor, nurse or pharmacist if any of these apply.

Some medicines can interfere with it. The NHS asks you to check before use if you take medicines for TB, epilepsy or HIV, the antifungal griseofulvin, lamotrigine, or the herbal remedy St John's wort.

Side effects and risks

The NHS says it has few side effects. The most notable are changes to periods, which may be lighter, more frequent or may stop, with spotting between cycles. Acne, mood changes, weight gain or altered sex drive are sometimes reported, but there is not enough evidence to say they are caused by the pill.

Fluid-filled sacs can form on the ovaries; they are not dangerous, usually do not need removing and often disappear without treatment, though they can occasionally cause pelvic pain. There may be a possible link with breast cancer, but the evidence is limited and any increase is very small.

Vomiting, diarrhoea and missed pills

The pill may not work if you vomit within 2 hours of a traditional pill, or within 3 to 4 hours of a desogestrel or drospirenone pill, or if you have severe watery diarrhoea. Contact a pharmacist, sexual health clinic, GP or NHS 111, and ask about emergency contraception.

For late or missed pills, the right action depends on how long it has been and the type of pill; the pack leaflet and a pharmacist can advise. The progestogen-only pill can affect how some emergency contraception works. An extra pill is unlikely to cause harm, though it may cause nausea, vomiting or vaginal bleeding.

STIs, fertility and supply

The progestogen-only pill does not stop you getting or passing on sexually transmitted infections, so condoms are recommended for that. When you stop it, it usually takes about 1 month for your chance of getting pregnant to return to what it was before.

Frequently asked

Questions people ask.

Quick, plain-English answers to the questions we hear most.

  • How late can I take the progestogen-only pill?

    Within 3 hours for a traditional pill, within 12 hours for desogestrel and within 24 hours for drospirenone, according to the NHS.

  • How effective is it?

    Over 99% with perfect use and 91% with typical use, which is about 9 pregnancies per 100 women a year.

  • Will my periods change?

    Often. They may become lighter, more frequent or stop altogether, and there may be spotting between periods.

  • Can I take it if I am breastfeeding?

    The NHS lists breastfeeding people among those who can take it.

  • Which medicines interfere with it?

    Medicines for TB, epilepsy or HIV, griseofulvin, lamotrigine and St John's wort. Check with a pharmacist or doctor.

  • What if I vomit after taking it?

    It may not work if you vomit within 2 hours of a traditional pill, or within 3 to 4 hours of desogestrel or drospirenone. Seek advice about emergency contraception.

  • Does it protect against STIs?

    No. Condoms are recommended for protection against infections.

  • Does it cause ovarian cysts?

    Fluid-filled sacs can form on the ovaries. The NHS says they are not dangerous and often disappear without treatment.

  • How long until I can get pregnant after stopping?

    Usually about 1 month for the chance of pregnancy to return to what it was before.

Where this comes from

Sources and checking.

This guide is for information, not medical advice.

Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.

Published 2026-10-03, next review 2027-10-03.