General and muscle symptoms
Aching all over the body: causes and when to see a GP
Aching muscles and joints throughout the body are common with infections, but when they last, or come with fatigue, stiffness or sleep disturbance, other explanations come into view. This guide compares the conditions the NHS describes and explains which patterns need assessment.
Last checked: 2026-10-10
Key facts
At a glance.
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Flu is a common reason
The NHS lists an aching body among the symptoms of flu, which comes on very quickly with a sudden high temperature, tiredness, dry cough, sore throat and headache.
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Long-term widespread pain
The NHS describes fibromyalgia as a long-term condition that causes pain all over the body, with increased sensitivity to pain, stiffness, sleep problems and fatigue.
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Morning stiffness in older adults
The NHS says the main symptom of polymyalgia rheumatica is muscle stiffness in the morning lasting longer than 45 minutes, affecting muscles around the shoulders, neck and hips. Most people diagnosed are over 65.
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Worse after exertion
The NHS lists symptoms getting worse after physical or mental activity as one of the 4 main symptoms of ME/CFS.
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More than a week
The NHS advises seeing a GP if pain and stiffness last for more than a week in the context of possible polymyalgia rheumatica.
Three questions that narrow it down
Aching "all over" can mean joint pain, muscle pain or simply feeling unwell. The cause is more likely to become clear if you consider how quickly it came on, how long it has lasted, and what else is going on: fever, fatigue, stiffness at a particular time of day, or poor sleep.
If it started suddenly alongside a fever and cough, an infection such as flu is the commonest explanation. If it has built up gradually, has been present for weeks or months and is accompanied by tiredness, sleep problems or stiffness, the conditions described below deserve consideration. None of them can be confirmed by a symptom list alone.
Flu and other infections
The NHS says flu symptoms come on very quickly and can include a sudden high temperature, an aching body, tiredness or exhaustion, a dry cough, a sore throat, a headache, difficulty sleeping and loss of appetite. It says cold and flu symptoms are similar but flu tends to be more severe, and that flu makes you feel exhausted and too unwell to carry on as normal.
For self-care the NHS suggests resting and sleeping, taking paracetamol or ibuprofen to lower the temperature and treat aches and pains, and drinking plenty of water. It advises getting urgent advice if you are 65 or over, pregnant, have a long-term condition or weakened immune system, feel very unwell or short of breath, or if symptoms do not improve after 7 days.
Longer-lasting causes
Fibromyalgia, polymyalgia rheumatica and ME/CFS all appear in the NHS pages on widespread aching. They are diagnosed by a clinician, usually after other causes have been considered, and the table sets out the main differences the NHS describes.
| Condition | Main features | Who is typically affected |
|---|---|---|
| Fibromyalgia | Pain all over the body, sensitivity to pain, muscle stiffness, sleep problems, fatigue, "fibro-fog", headaches, IBS; symptoms changeable | More common in women; typically develops between 25 and 55 |
| Polymyalgia rheumatica | Pain, stiffness and inflammation in muscles around the shoulders, neck and hips; morning stiffness lasting more than 45 minutes; extreme tiredness, loss of appetite, weight loss, depression | Most people diagnosed are over 65; very rare under 50; more common in women |
| ME/CFS | Extreme tiredness, sleep problems, problems with thinking and concentration, symptoms worsening after activity; some have pain or flu-like aching | Can affect anyone including children |
| Premenstrual dysphoric disorder | Severe premenstrual symptoms that can include headaches and joint and muscle pain | People who have periods |
How clinicians tell them apart
There is no specific test for fibromyalgia, according to the NHS, which says it is hard to diagnose because symptoms can be similar to several other conditions. ME/CFS is likewise diagnosed from symptoms and by ruling out other conditions, with a GP asking about your history and possibly arranging blood and urine tests. The NHS says polymyalgia rheumatica can be difficult to diagnose because symptoms resemble many other conditions, including rheumatoid arthritis, which need to be ruled out first.
Because polymyalgia rheumatica is linked with temporal arteritis, the NHS gives specific warnings. A new or frequent headache that usually develops suddenly, a tender scalp, pain in the jaw muscles or tongue when eating or talking, and problems with sight such as double vision or loss of vision are reasons to contact a GP immediately or use NHS 111, because it can lead to stroke or blindness if not treated quickly.
What helps and when to be seen
The NHS says there is currently no cure for fibromyalgia, but treatments can relieve symptoms. These tend to be a combination of lifestyle changes such as exercise programmes and relaxation, talking therapies such as CBT and ACT, and medicines such as antidepressants, and it highlights exercise in particular as helping reduce pain. For ME/CFS it describes energy management, CBT and medicines for symptoms such as pain and sleep problems. Polymyalgia rheumatica is treated mainly with the steroid prednisolone, usually for 12 months to 2 years.
See a GP if aching lasts more than a week without an obvious cause such as flu, if it comes with marked fatigue, weight loss, fever, stiffness lasting more than 45 minutes in the morning, or if it is affecting sleep or daily activities. A symptom diary covering what you feel, when and for how long makes the appointment more useful.
Frequently asked
Questions people ask.
Quick, plain-English answers to the questions we hear most.
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Why do I ache all over when I have flu?
The NHS lists an aching body among the usual symptoms of flu, along with a sudden high temperature and tiredness. It suggests resting, drinking plenty of water and taking paracetamol or ibuprofen to ease aches and pains.
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When should aching worry me?
The NHS advises a GP review if pain and stiffness last more than a week with no clear cause, and urgent advice if flu symptoms come with breathlessness, or do not improve after 7 days, or if you are in an at-risk group.
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What is fibromyalgia?
The NHS says it is a long-term condition that causes pain all over the body, with other symptoms such as stiffness, sleep difficulty, fatigue and problems with concentration. It is more common in women, usually developing between 25 and 55.
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Is there a test for fibromyalgia?
No. The NHS says there is no specific test and that symptoms can be similar to a number of other conditions, which is why it can be difficult to diagnose.
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What is polymyalgia rheumatica?
The NHS describes it as a condition causing pain, stiffness and inflammation in muscles around the shoulders, neck and hips, with morning stiffness lasting longer than 45 minutes. It is mostly seen in people over 65.
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Why is a headache with muscle aches in an older person urgent?
Because the NHS says up to 1 in 5 people with polymyalgia rheumatica develop temporal arteritis, which can cause a new headache, scalp tenderness, jaw pain and sight problems and needs immediate attention.
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Can ME/CFS cause body aches?
The NHS says some people with ME/CFS may also have pain in different parts of the body or flu-like symptoms such as aching joints or muscles. The main symptom is extreme tiredness.
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Can premenstrual symptoms cause aching?
The NHS says the more severe premenstrual dysphoric disorder can include headaches and joint and muscle pain, with other mood and sleep symptoms.
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Do I need blood tests?
A GP may arrange blood tests to look for other causes. The NHS mentions blood and urine tests in the assessment of ME/CFS, and says conditions such as rheumatoid arthritis need to be ruled out when polymyalgia rheumatica is suspected.
Where this comes from
Sources and checking.
This guide is for information, not medical advice.
Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.
Published 2026-10-10, next review 2027-10-10.
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NHS: Flu, https://www.nhs.uk/conditions/flu/ , retrieved October 2026
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NHS: Fibromyalgia, https://www.nhs.uk/conditions/fibromyalgia/ , retrieved October 2026
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NHS: Polymyalgia rheumatica, https://www.nhs.uk/conditions/polymyalgia-rheumatica/ , retrieved October 2026
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NHS: Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), https://www.nhs.uk/conditions/chronic-fatigue-syndrome-cfs/ , retrieved October 2026
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NHS: PMS (premenstrual syndrome), https://www.nhs.uk/conditions/pre-menstrual-syndrome/ , retrieved October 2026
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