Menopause and hormones
Early menopause: symptoms, causes, HRT and support in the UK
Early menopause is when periods stop before the age of 45, and premature menopause is when this happens before 40. It can be natural or caused by treatment such as chemotherapy or surgery. This guide explains symptoms, causes, why hormone replacement is usually advised, what it means for fertility and bone and heart health, and where to find support.
Last checked: 2026-10-11
Key facts
At a glance.
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Definitions
The NHS says early menopause is when you stop having regular periods before the age of 45, and premature menopause is when this happens before the age of 40.
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Natural or caused by treatment
The NHS says it can happen naturally or be caused by treatment for other conditions, including radiotherapy, chemotherapy, certain hormone medicines and surgery to remove the ovaries.
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Hormone replacement matters
The NHS says it is important to replace missing hormones if menopause starts before 45, because there is a higher chance of problems with bones and heart.
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Health risks
The NHS says you will have a higher chance of conditions such as osteoporosis and cardiovascular disease.
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Fertility
The NHS says it may be harder to get pregnant, and that some people may be able to have children through IVF using frozen eggs or donor eggs.
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Specialist help
If treatment and lifestyle changes do not help, the NHS says you can be referred to a specialist menopause centre.
What early and premature menopause mean
Menopause is when periods stop because of lower hormone levels. The NHS says it usually affects women between 45 and 55, and that it can affect anyone who has periods. NICE describes it as the time when the body stops producing eggs, and notes that it can happen as part of ageing, usually between 45 and 55, but sometimes earlier.
When it happens before 45 it is called early menopause, and before 40 it is called premature menopause. Both can come about naturally, or as a result of treatment or surgery. Because, as the NHS notes, an early start brings a higher chance of problems with bones and heart, an early start has consequences beyond the symptoms people notice day to day, which is why diagnosis and treatment matter.
You may also hear the term premature ovarian insufficiency, which describes ovaries that stop working normally before 40. It is covered in a separate guide linked below.
Symptoms
The NHS says the main symptom is not having your period regularly, or periods stopping completely before 45. NICE adds that periods may become heavy or irregular before they stop, and that symptoms can vary from barely noticeable to strongly affecting everyday life.
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Hot flushes and night sweats.
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Vaginal dryness.
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Difficulty sleeping.
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Low mood or anxiety.
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Reduced sex drive.
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Problems with memory or concentration.
Causes and risk factors
According to the NHS, you have a higher chance of early or premature menopause if it runs in your family. It is also more likely if you started your periods early, smoke or are underweight. For many people no clear reason is found.
Treatment for other conditions can bring on menopause. The NHS lists radiotherapy or chemotherapy, certain hormone medicines and surgery to remove the ovaries. NICE also mentions an inherited condition or an unknown reason. When menopause follows surgery or cancer treatment it can start abruptly, and symptoms are often more sudden. The surgical menopause guide linked below covers this in more detail.
How it is recognised
The NHS advises seeing a GP if you think you have menopause symptoms. It says that if you are under 45 and having menopause symptoms, a GP may sometimes do blood tests. A GP will usually ask about your periods, symptoms, medical history and family history and may consider other explanations for missed periods.
Being told that menopause has started when you are in your 30s or early 40s can be a shock, especially if you had hoped to have children. It is reasonable to ask for time to take in the information and for a follow-up appointment to discuss the next steps.
Treatment and why replacing hormones is advised
The NHS says the main treatments are medicines such as the combined contraceptive pill or hormone replacement therapy (HRT) to replace hormones that are at low levels. It stresses that this is important if menopause starts before 45, because of the higher chance of problems with bones and heart.
The NHS notes that if you have had certain types of cancer, such as certain types of breast cancer, you may not be able to have hormone treatments. In that case your specialist team can discuss other ways to manage symptoms and protect your health.
Lifestyle changes can support treatment. The NHS suggests exercising regularly and eating calcium-rich food such as yoghurt. NICE encourages shared decisions: your healthcare professional should explain the benefits and risks of each option so you can work out together what suits you, taking into account your age, medical history and preferences.
If treatment and lifestyle changes do not help and you still have symptoms, the NHS says you can be referred to a specialist menopause centre, and points to the British Menopause Society website for NHS and private specialists.
Fertility and emotional wellbeing
The NHS says early or premature menopause means you may find it harder to get pregnant. You may be able to have children through IVF using your own frozen eggs or donor eggs, and there are other routes such as surrogacy or adoption. The Human Fertilisation and Embryology Authority provides information about fertility treatment.
The NHS recognises that early menopause can affect mental health as well as physical health, and says you can refer yourself to NHS talking therapies for anxiety and depression without seeing a GP first. The Daisy Network, named by both NHS and NICE, is a charity specifically for premature menopause.
NHS care or a private menopause specialist
On the NHS, early menopause is usually managed by a GP, with referral to a specialist menopause service or gynaecology or endocrinology if needed.
Some people also see a private menopause specialist, usually for a quicker appointment or more time to discuss options. The British Menopause Society lists both NHS and private specialists. In either setting, ask how often your treatment will be reviewed, because needs can change over time.
Frequently asked
Questions people ask.
Quick, plain-English answers to the questions we hear most.
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What age is early menopause?
The NHS defines early menopause as periods stopping before the age of 45, and premature menopause as before the age of 40.
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What are the symptoms of early menopause?
The NHS lists periods becoming irregular or stopping, hot flushes and night sweats, vaginal dryness, difficulty sleeping, low mood or anxiety, reduced sex drive and problems with memory or concentration.
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What causes early menopause?
It can run in families and is more likely if you started periods early, smoke or are underweight. Radiotherapy, chemotherapy, certain hormone medicines and ovary removal surgery can also cause it, according to the NHS.
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Should I take HRT if I have early menopause?
The NHS says it is important to replace missing hormones if menopause starts before 45 because of the higher chance of bone and heart problems. Some people with certain cancers cannot take hormones, so discuss it with your doctor.
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Does early menopause affect fertility?
Yes. The NHS says it may be harder to get pregnant. IVF with your own frozen eggs or donor eggs may be possible, and surrogacy and adoption are other routes.
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Will a GP test for it?
The NHS says that if you are under 45 and having menopause symptoms, a GP may sometimes do blood tests.
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What health problems can early menopause cause?
The NHS says a higher chance of osteoporosis and cardiovascular disease, and effects on mental health.
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Where can I find support?
The NHS points to The Daisy Network for premature menopause, the HFEA for fertility treatment, Adoption UK and Surrogacy UK. NICE also lists Menopause Matters and the Menopause Charity.
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Can lifestyle changes help?
The NHS suggests regular exercise and eating calcium-rich food such as yoghurt, alongside medicines.
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What if treatment does not work?
The NHS says you can be referred to a specialist menopause centre if treatment and lifestyle changes do not help.
Where this comes from
Sources and checking.
This guide is for information, not medical advice.
Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.
Published 2026-10-11, next review 2027-10-11.
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NHS: Early or premature menopause, https://www.nhs.uk/conditions/early-menopause/ , retrieved October 2026
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NICE: Menopause: identification and management (NG23), information for the public, https://www.nice.org.uk/guidance/ng23/informationforpublic , retrieved October 2026
Related guides
Keep reading.
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Premature ovarian insufficiency
Ovaries that stop working normally before 40.
Read guide -
Menopause
An overview of the menopause at any age.
Read guide -
Hormone replacement therapy
How HRT works and who it suits.
Read guide -
Surgical menopause
Menopause after ovary removal.
Read guide -
Osteoporosis
Bone thinning, a risk after early menopause.
Read guide