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Medicine guide

Cyclizine: nausea, vertigo and travel sickness tablets

Cyclizine is an anti-sickness medicine that also helps with dizziness and vertigo. It is used for travel sickness, Meniere's disease, sickness from radiotherapy and morning sickness in pregnancy, and the tablets are sold in pharmacies or prescribed.

Last checked: 2026-10-03

Key facts

At a glance.

  • Uses

    Nausea, vomiting, dizziness and vertigo, including travel sickness, Meniere's disease, radiotherapy and pregnancy sickness.

  • Form

    Tablets swallowed with water.

  • Supply

    From pharmacies or on prescription.

  • Age

    Most adults and children aged 6 and over can take it.

  • Alcohol

    Do not drink alcohol; it can cause heavy drowsiness and breathing problems.

  • Breastfeeding

    Not usually used because of the risk of side effects in the baby.

What cyclizine treats

Cyclizine treats feeling sick and being sick, and it helps dizziness and vertigo. The NHS lists sickness when travelling, Meniere's disease, side effects of radiotherapy and morning sickness in pregnancy among the causes it can be used for.

It usually comes as tablets that you swallow with water, which can be bought from pharmacies or prescribed. The NHS page does not list brand names or a time to onset.

How it is taken

The NHS does not give a fixed dose; your pharmacist or doctor will tell you how much to take and for how long, and the pack leaflet gives the details for the product you have.

If you miss a dose, skip it and take the next at the usual time. Taking an extra dose can be dangerous, so call NHS 111 if you take more than prescribed.

Because the tablets can be bought from a pharmacy as well as prescribed, it is worth reading the leaflet in your pack every time and asking the pharmacist if anything in it does not fit your situation. Tell them about long-term conditions and every other medicine you use, since cyclizine has more interactions than many people expect.

Cyclizine treats the symptom rather than the cause. If sickness or dizziness keeps coming back, lasts for days, or comes with severe headache, confusion, repeated vomiting or an inability to keep fluids down, that calls for medical assessment rather than longer self-treatment.

Who should not take it

Most adults and children aged 6 and over can take cyclizine. It is not suitable if you have high blood pressure, glaucoma, epilepsy, liver problems or heart failure, conditions that affect urination such as an enlarged prostate, or a bowel obstruction, or if you have previously reacted to it. Tell the prescriber or pharmacist about these before starting.

Side effects

Common effects include constipation or diarrhoea, dry mouth, headaches, blurred vision and drowsiness. Do not drive or use machinery if you have blurred vision or feel drowsy.

Rare serious effects are anaphylaxis (swollen throat or tongue, raised itchy rash, breathing difficulty), muscle twitches, spasms or seizures, heart rhythm problems or palpitations, unusual bleeding and jaundice. Call 999 for anaphylaxis and NHS 111 for other serious effects.

Suspected side effects can be reported through the Yellow Card scheme.

Alcohol and medicines that do not mix

The NHS says not to drink alcohol while taking cyclizine, because it can make you very drowsy and could cause breathing problems.

Medicines that should not be taken with it include the antidepressant amitriptyline, the bladder medicines oxybutynin and solifenacin, sleep aids such as diphenhydramine and zolpidem, the muscle relaxant baclofen, strong painkillers such as codeine and morphine, and anxiety medicines such as diazepam. Ask a pharmacist to check your own list.

Pregnancy and breastfeeding

Cyclizine can be used in pregnancy, with doctors prescribing the lowest effective dose. It is not usually used while breastfeeding because it could cause side effects in a baby, though a doctor may recommend it for a short time if the benefits outweigh the risks.

Food, driving and what else can help

You can eat as normal while taking cyclizine. Avoid driving while drowsy or if your vision is blurred.

Domperidone and metoclopramide are other prescription anti-sickness options, and their guides explain how they differ. For vertigo, the cause matters more than the symptom, so persistent dizziness is worth discussing with a doctor.

Frequently asked

Questions people ask.

Quick, plain-English answers to the questions we hear most.

  • What is cyclizine used for?

    The NHS lists nausea, vomiting, dizziness and vertigo, including with travel, Meniere's disease, radiotherapy and pregnancy sickness.

  • Can I buy it without a prescription?

    The tablets are available from pharmacies or on prescription.

  • Can I drink alcohol with cyclizine?

    No. Alcohol can make you very drowsy and could cause breathing problems.

  • Does it cause drowsiness?

    Yes, drowsiness is a common effect. Do not drive or use machinery if you are drowsy or have blurred vision.

  • Who should avoid it?

    People with high blood pressure, glaucoma, epilepsy, liver problems, heart failure, an enlarged prostate or a bowel obstruction should check first.

  • Can I use it in pregnancy?

    Yes. Doctors prescribe the lowest effective dose.

  • Is it safe while breastfeeding?

    It is not usually used, but a doctor may recommend short-term use if benefits outweigh risks.

  • Which medicines should I avoid with it?

    The NHS names amitriptyline, oxybutynin, solifenacin, diphenhydramine, zolpidem, baclofen, codeine, morphine and diazepam.

  • What if I miss a dose?

    Skip it and take your next dose at the usual time.

  • What if I take too much?

    It can be dangerous. Call NHS 111 if you take more than prescribed.

Where this comes from

Sources and checking.

This guide is for information, not medical advice.

Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.

Published 2026-10-03, next review 2027-10-03.