Medicine guide
Propranolol: uses, doses, side effects and cautions
Propranolol is a beta blocker with an unusually wide range of uses, from high blood pressure and irregular heartbeat to the physical symptoms of anxiety and migraine prevention. Doses vary a lot between uses, so this guide sets out the figures the NHS publishes alongside side effects and safety points.
Last checked: 2026-10-03
Key facts
At a glance.
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Medicine type
A beta blocker. Brands listed by the NHS include Bedranol, Beta-Prograne and Half Beta-Prograne.
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Forms
Tablets, slow-release capsules and oral liquid.
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Onset
It usually starts working in a few hours; for heart conditions or high blood pressure full effect can take 2 to 3 weeks.
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Age
Most adults and children aged 12 and over can take it.
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Stopping
Doses are usually reduced gradually over 1 to 2 weeks rather than stopped abruptly.
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Breastfeeding
It passes into breast milk in tiny amounts and has not been known to cause side effects in breastfed babies.
What propranolol is used for
The NHS lists high blood pressure, irregular heartbeats including atrial fibrillation, prevention of further heart problems after a heart attack, angina, anxiety symptoms, migraine prevention and thyrotoxicosis as uses. It is a beta blocker and available only on prescription.
The NHS explains that it slows the heart rate and makes it easier for the heart to pump blood around the body. For anxiety, that is why it can ease physical symptoms such as sweating and trembling; it does not treat the worry itself.
Forms and the doses the NHS publishes
Standard tablets and liquid are quick-release and taken several times a day; slow-release capsules are taken once daily. The NHS gives these typical adult starting figures, and says doses are usually lower for people over 65 or with kidney or liver problems.
| Use | Typical dose |
|---|---|
| High blood pressure | 80 mg twice a day, rising to a maximum of 160 mg twice a day |
| Migraine prevention or angina | 40 mg two or three times a day, up to 240 mg a day |
| Irregular heartbeat | 10 mg to 40 mg three or four times a day |
| Anxiety | 40 mg once a day, which can be increased to 40 mg three times a day |
| Thyrotoxicosis | 10 mg to 40 mg three or four times a day |
How to take it and how long for
Swallow tablets and capsules whole with water. Measure liquid with the syringe or spoon supplied. Propranolol does not usually upset the stomach, so food does not matter. The first doses can cause dizziness, and bedtime dosing is suggested.
Duration depends on the reason: heart conditions may need lifelong treatment, anxiety is generally short term, and migraine prevention can last several months to years. If you miss a dose, take it when you remember unless the next is nearly due; never double up. After an overdose with slow heart rate, breathing problems, dizziness, seizures or chest pain, call 999 or go to A&E.
Talk to your doctor before stopping. The NHS says doses are usually reduced gradually over one to two weeks.
Who may not be able to take it
Tell the prescriber if you have had an allergic reaction to propranolol, have low blood pressure, a slow heart rate, worsening heart failure, a history of depression or self-harm thoughts, diabetes, liver or kidney problems, severe circulation problems in the limbs such as Raynaud phenomenon, metabolic acidosis, lung disease or asthma, or an adrenal gland tumour called phaeochromocytoma. Pregnancy, planning pregnancy and breastfeeding should also be raised.
Side effects and what helps
Headaches, tiredness, dizziness, weakness, cold hands and feet, sickness, diarrhoea and sleep problems with nightmares are the common ones. The NHS says they are usually mild and short lived. For cold fingers, warm running water and massage can help, and smoking and caffeine make it worse. For sleep problems, avoid large evening meals, alcohol, tea and coffee.
Easy bruising, or shortness of breath with a worsening cough, swollen ankles or an irregular heartbeat, should be reported promptly to a doctor or NHS 111. Call 999 for new or worsening chest pain or signs of a serious allergic reaction.
Interactions, alcohol and driving
Named interacting medicines include amiodarone, digoxin and flecainide, other blood pressure medicines, nitrates, antidepressants, baclofen, tamsulosin, levodopa, asthma and COPD medicines, insulin and diabetes medicines, nasal decongestants and cold remedies, ephedrine, noradrenaline and adrenaline, NSAIDs such as ibuprofen, diclofenac and naproxen, and rizatriptan. There is little information on herbal remedies.
Avoid alcohol if you feel dizzy or weak, and do not drive until these have passed.
Pregnancy and breastfeeding
You can take propranolol during pregnancy, but it can sometimes affect the baby's growth, and the NHS recommends extra growth scans from around week 32. Propranolol passes into breast milk in tiny amounts and has not been known to cause side effects in breastfed babies. There is no evidence it affects fertility. Report suspected side effects via the Yellow Card scheme.
Frequently asked
Questions people ask.
Quick, plain-English answers to the questions we hear most.
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Why is propranolol used for anxiety?
It eases physical symptoms such as a pounding heart, sweating and trembling. It does not treat the underlying anxiety itself.
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How quickly does it work?
The NHS says it usually starts to work in a few hours. For heart conditions or high blood pressure it can take 2 to 3 weeks to work fully.
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Can I take it with asthma?
Asthma and lung disease are on the NHS list of reasons to tell the prescriber first, because propranolol may not be suitable.
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Can I stop it suddenly?
No. The NHS says doctors usually reduce the dose gradually over 1 to 2 weeks.
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What is the migraine dose?
The NHS gives 40 mg two or three times a day, up to 240 mg a day, as typical for migraine or angina. Your prescriber sets your dose.
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Can children take it?
Most adults and children aged 12 and over can; a doctor may prescribe it for younger children with high blood pressure, though this is unlicensed.
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Is it safe in pregnancy?
You can take it, with extra growth scans from around 32 weeks because it can sometimes affect baby's growth.
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Does it affect sleep?
Sleep problems and nightmares are listed. Avoid big evening meals, alcohol, tea and coffee.
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Can I take ibuprofen with it?
NSAIDs including ibuprofen, diclofenac and naproxen are named as interacting. Ask a pharmacist first.
Where this comes from
Sources and checking.
This guide is for information, not medical advice.
Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.
Published 2026-10-03, next review 2027-10-03.
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NHS - Propranolol - about propranolol, https://www.nhs.uk/medicines/propranolol/about-propranolol/ , retrieved October 2026
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NHS - Propranolol - how and when to take it, https://www.nhs.uk/medicines/propranolol/how-and-when-to-take-propranolol/ , retrieved October 2026
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NHS - Propranolol - pregnancy and breastfeeding, https://www.nhs.uk/medicines/propranolol/pregnancy-breastfeeding-and-fertility-while-taking-propranolol/ , retrieved October 2026
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MHRA Yellow Card scheme - the UK system for reporting suspected side effects, https://yellowcard.mhra.gov.uk/ , retrieved October 2026
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