Medicine guide
Metoprolol: uses, doses, side effects and cautions
Metoprolol is a beta blocker that slows the heart rate. It treats high blood pressure and irregular heartbeat, prevents angina and migraine, and is used for thyrotoxicosis symptoms. The NHS lists doses by condition and notes it is among the preferred options for blood pressure while breastfeeding.
Last checked: 2026-10-03
Key facts
At a glance.
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Medicine type
A beta blocker that slows the heart rate.
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Forms
Tablets in 25 mg, 50 mg and 100 mg strengths; some have score lines. It can also be given by injection in hospital.
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Frequency
Usually once or twice a day, sometimes up to four times a day.
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First dose
May cause dizziness, so your doctor may advise taking it before bedtime.
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Age
Most adults and children can take it; it is sometimes used for high blood pressure in children under 12.
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Surgery
Tell your doctor before an operation needing general anaesthetic.
What metoprolol is for
The NHS lists high blood pressure, conditions that cause an irregular heartbeat, prevention of heart disease, heart attacks and strokes, prevention of angina chest pain, migraine prevention and reducing symptoms of thyrotoxicosis. It belongs to the beta blocker class and slows the heart rate so the heart pumps more easily. Tablets are prescription only.
Doses published by the NHS
These are the typical adult figures given. Your own dose depends on your condition and response, so follow your prescriber.
| Use | Typical dose |
|---|---|
| High blood pressure | 50 mg to 100 mg twice a day |
| Angina (chest pain) | 50 mg to 100 mg two to three times a day |
| Irregular heartbeat | 50 mg two to three times a day |
| Migraine prevention | 50 mg to 100 mg twice a day |
| Thyrotoxicosis | 50 mg four times a day |
Taking it day to day
Swallow tablets whole with water, with or without food. Space multiple daily doses evenly. If the first dose makes you dizzy, taking it at bedtime is suggested; if well tolerated, you can then switch to the morning.
For heart conditions and high blood pressure you may need it for the rest of your life, while migraine prevention may last several months to years. If you miss a dose, take it when you remember unless the next is near, in which case skip it. Never double up. Call NHS 111 if you take more than prescribed; symptoms of too much include slow heart rate, breathing difficulty, dizziness and trembling.
Stopping metoprolol suddenly can make your condition worse, so talk to your doctor first. The medicine leaves the body in one to two days.
Who needs to check first
Say if you have ever had an allergic reaction to metoprolol, low blood pressure or a slow heart rate, lung disease or severe asthma, metabolic acidosis, an overactive thyroid (metoprolol may hide its warning signs), severe circulation problems such as Raynaud syndrome, or liver conditions. Tell your doctor before any surgery needing general anaesthetic, as blood pressure can fall too far with some anaesthetics.
Side effects
Headaches, tiredness, dizziness, nausea, stomach pain, vomiting and diarrhoea are the main ones, typically mild and short lived. Rest and drink fluids for headaches, avoid driving or machinery when tired or dizzy, and avoid smoking and caffeine if your fingers and toes feel cold. Keep meals simple for nausea.
Call NHS 111 or a doctor for heart problems, thyroid symptoms or unusual bruising. Call 999 for chest pain that does not settle, severe breathlessness or wheezing, or signs of a serious allergic reaction.
Interactions and alcohol
Named medicines: other blood pressure medicines, antidepressants, nitrates, baclofen, tamsulosin, co-careldopa and levodopa, NSAIDs such as ibuprofen, diabetes medicines, and ephedrine, noradrenaline and adrenaline. Some herbal remedies, especially ones that lower blood pressure, may be a problem. The NHS advises against alcohol as it may worsen symptoms such as dizziness.
Pregnancy and breastfeeding
You may take metoprolol in pregnancy, but it can sometimes affect the baby's growth and extra growth scans are usual, generally from 32 weeks. It is among the preferred options for high blood pressure while breastfeeding a healthy baby, as it passes into breast milk in very small amounts and has not been known to cause side effects. No evidence shows it reduces fertility. Report suspected side effects via the Yellow Card scheme.
Frequently asked
Questions people ask.
Quick, plain-English answers to the questions we hear most.
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Why might I take the first dose at bedtime?
The first dose can make you dizzy. If you tolerate it, you can usually move to the morning.
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How often do I take metoprolol?
The NHS says usually once or twice a day, sometimes up to four times a day depending on the condition.
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Can metoprolol prevent migraine?
It is used for migraine prevention. The NHS gives 50 mg to 100 mg twice a day as typical; prevention may last several months to years.
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Can I stop it suddenly?
No. Stopping suddenly can make your condition worse, so talk to your doctor first.
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Should I tell my surgeon?
Yes. The NHS says to tell your doctor before surgery needing general anaesthetic.
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Is it safe while breastfeeding?
It is one of the preferred options for blood pressure in a healthy baby, because only very small amounts pass into milk.
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Can I take it with asthma?
Severe asthma or lung disease is a reason to check with your prescriber before starting.
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Is alcohol a problem?
The NHS advises not drinking alcohol if it makes dizziness or other symptoms worse.
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Can children take it?
Most adults and children can; it is sometimes used for blood pressure in children under 12.
Where this comes from
Sources and checking.
This guide is for information, not medical advice.
Your GP or consultant knows your history and can tell you which parts apply to you. If your symptoms are severe, rapidly worsening, or come with red-flag features, seek urgent medical care. Figures and availability change, so treat them as a guide and confirm with the provider.
Published 2026-10-03, next review 2027-10-03.
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NHS - Metoprolol - about metoprolol, https://www.nhs.uk/medicines/metoprolol/about-metoprolol/ , retrieved October 2026
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NHS - Metoprolol - how and when to take it, https://www.nhs.uk/medicines/metoprolol/how-and-when-to-take-metoprolol/ , retrieved October 2026
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NHS - Metoprolol - pregnancy and breastfeeding, https://www.nhs.uk/medicines/metoprolol/pregnancy-breastfeeding-and-fertility-while-taking-metoprolol/ , retrieved October 2026
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MHRA Yellow Card scheme - the UK system for reporting suspected side effects, https://yellowcard.mhra.gov.uk/ , retrieved October 2026
Related guides
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Angina
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Bisoprolol
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