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Pathology · London

HPV genotyping test - private in London.

High-risk HPV testing for cervical, anal and oropharyngeal risk. Type-specific results for 16, 18, 31, 33, 45, 52 and 58 - the seven types behind most HPV-driven cancers. Booked in one working day.

  • Clinically reviewed
  • Vetted CQC-registered clinics
  • Reply within one working day
  • Free
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A private pathology laboratory in London processing HPV genotyping samples

What the test is

A nucleic acid amplification test for high-risk HPV.

It detects DNA or mRNA from 14 high-risk HPV types. Genotyping goes one step further, telling you which specific type is present - and whether it is one of the two behind most cervical cancers.

14 high-risk types

HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68. Between them they cause almost all cervical, anal and HPV-driven oropharyngeal cancers.

HPV 16 and 18

The two types that cause around 70 percent of cervical cancers and most HPV-related anal and oropharyngeal cancers. Type-specific reporting matters.

DNA versus mRNA

DNA tests show the virus is present. mRNA tests (Aptima) target E6 and E7 transcripts, a marker of active oncogenic expression, and can reduce false positives from transient infection.

Who benefits

Who is HPV genotyping for?

Some patients benefit from a first-line screen, others from targeted follow-up after an abnormal result.

  • Women 25 to 65

    Cervical screening, particularly with prior LSIL or ASC-US on Pap cytology.

  • Men who have sex with men

    Anal HPV screening, especially for HIV-positive patients where anal cancer risk is higher.

  • Oropharyngeal risk

    Head and neck cancer risk assessment, particularly with unexplained cervical lymph nodes.

  • Post-treatment surveillance

    After treatment for CIN2 or CIN3, follow-up genotyping shows whether the causative type has cleared.

  • Vaccinated adults

    Peace of mind for those concerned about types not covered by earlier vaccines.

  • New partners

    A baseline before a new relationship, alongside a full STI screen.

Sample types

Where the sample comes from.

HPV testing is site-specific. A cervical result tells you nothing about anal or oral HPV, and vice versa.

  • Cervical

    Self-collected vaginal swab or clinician-collected liquid-based cytology sample.

  • Anal

    Clinician-collected anal canal swab, usually paired with anal cytology.

  • Oropharyngeal

    Throat swab or oral gargle sample for head and neck risk assessment.

  • Penile

    Penile shaft swab, often included with a broader male STI panel.

Testing options

The main assay platforms.

London laboratories run one or more of these. We match the assay to the question.

  • Hologic Aptima HPV

    mRNA test targeting E6 and E7 transcripts of 14 high-risk types. Higher specificity than DNA-only tests.

  • Roche cobas HPV

    HPV DNA with concurrent 16 and 18 genotyping in a single result.

  • Cepheid Xpert HPV

    Cartridge-based platform with same-day turnaround, useful for rapid triage.

  • Papillocheck genotyping

    Extended panel covering 24 hrHPV types, useful for detailed surveillance.

Interpretation

What each result actually means.

Genotype and persistence matter more than a single positive.

  1. 01 Negative

    No high-risk HPV detected

    Very low risk of cervical cancer over the next 5 years. Return to routine screening intervals.

  2. 02 hrHPV +

    Positive, non-16 or 18

    Cytology follow-up. If cytology is normal, repeat HPV in 12 months to check for persistence.

  3. 03 HPV 16 or 18

    Highest-risk types

    Direct colposcopy referral. These two types cause the majority of cervical cancers.

  4. 04 Persistent

    Same type at 12 months

    Colposcopy referral. Persistence, not one-off positivity, drives cancer risk.

Cost in London

Indicative pricing, no bait figures.

Ranges across our vetted London partners. We come back with firm quotes across two or three options.

In short

Most HPV genotyping in London: £150 to £350, reported in 3 to 7 days.

Test Indicative range
Basic hrHPV (positive or negative) £150–£220
hrHPV with 16 and 18 genotyping £220–£320
Extended 14-type genotyping £280–£450
Self-collect vaginal kit £120–£250
Anal HPV genotyping (clinician-collected) £220–£380
Combined HPV plus liquid-based cytology (Pap) £280–£450

Where to get tested

A small panel of London clinics.

Sexual health, gynaecology, colposcopy and private pathology. Introductions made privately.

  • The Doctors Laboratory (TDL Direct)

    Central London laboratory offering HPV genotyping through partner clinics.

  • Randox Health

    City and West End clinics with self-collect and clinician-collected options.

  • 56 Dean Street

    NHS-affiliated sexual health service in Soho, strong on anal HPV.

  • HCA The Wellington

    St John's Wood colposcopy and gynaecology with rapid HPV workup.

  • Chelsea and Westminster Private

    Consultant-led gynaecology and sexual health, integrated cytology.

  • Chelsea Colposcopy

    Dedicated colposcopy clinic for HPV-positive triage and CIN treatment.

  • London Women's Clinic

    Harley Street women's health with combined HPV and Pap testing.

  • HCA London Bridge

    Broad diagnostics including anal HPV for high-risk MSM patients.

HPV vaccination

Vaccination alongside testing.

Vaccination and testing are complementary, not alternatives.

Gardasil 9

Covers HPV 6, 11, 16, 18, 31, 33, 45, 52 and 58. Adults up to age 45 are eligible privately, per the licensed indication. Three-dose schedule at 0, 2 and 6 months for adults.

NHS routine programme

Offered to girls and boys aged 12 to 13. Catch-up available up to age 25 for those who missed it, and to MSM up to age 45 through sexual health clinics.

Frequently asked

HPV genotyping, answered.

Self-sampling, insurance, repeat intervals, vaccinated adults, anal testing and partners.

  • How accurate is a self-collected vaginal swab?

    Very accurate. Self-collected vaginal swabs perform comparably to clinician-collected samples for high-risk HPV detection and are now endorsed by NHS cervical screening for those who decline a speculum. Cytology, if triggered, still needs a clinician sample.

  • Will my insurance cover HPV genotyping?

    Most PMI policies cover HPV testing when clinically indicated, for example after an abnormal Pap or in colposcopy follow-up. Screening-only tests without symptoms are usually self-funded. We confirm coverage before booking.

  • How often should I repeat the test?

    If negative, every 5 years for routine cervical screening from age 25 to 65. If positive with normal cytology, repeat in 12 months. Post-treatment for CIN, 6 and 18 months is typical. Your clinician will individualise this.

  • I have been vaccinated. Do I still need testing?

    Yes. Gardasil 9 covers 9 types but not all high-risk types, and earlier vaccines cover fewer. Cervical screening continues for vaccinated women, and testing is worthwhile if there is a specific concern.

  • Who should have an anal HPV test?

    Men who have sex with men, particularly those living with HIV, benefit most given higher anal cancer risk. Some women with a history of vulvar or cervical HPV disease may also be offered anal screening. Discuss with a sexual health specialist.

  • Should my partner be tested?

    There is no approved routine HPV test for men outside of anal or oropharyngeal indications. Most HPV clears without treatment. A partner discussion is more useful than a partner test in most cases.

One working day

Book a private HPV genotyping test in London.

Tell us what is going on. We reply within one working day with a clinic, a clinician and a firm quote. Free.

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