Health condition · Clinically reviewed
Chondral injury, focal defects, modern cartilage repair and the road back to sport.
Cartilage does not heal on its own. A stepped plan from conservative care to biological repair, alignment surgery and structured rehab restores function for most patients.
Why trust this guide
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Clinically reviewed
Written by our editorial team and reviewed by a registered UK clinician before publication.
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Sourced from guidance
Checked against BASK, BOA, NICE and peer-reviewed cartilage-repair sources listed at the end.
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Current for 2026
Reflects modern UK practice including MACI, minced cartilage, subchondroplasty and cartilage rehab pathways.
Key facts
Chondral injury at a glance.
The essentials in plain English. What it is, where it happens, how it is graded, and how it is treated in the UK today. For the broader hub on cartilage damage across joints, see our related cartilage injury guide.
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What it is
A focal defect in the articular cartilage that lines a joint. The knee accounts for roughly 90 per cent of cases seen in specialist practice.
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Where it happens
Most commonly the medial and lateral femoral condyles, the patellofemoral joint, the talar dome (ankle), and less often the shoulder, hip, elbow or wrist.
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Why it matters
Cartilage does not heal on its own. Untreated focal defects can enlarge, alter joint mechanics and lead on to early osteoarthritis.
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Classification
Outerbridge I to IV and ICRS 0 to 4 grade the depth and size of the lesion and guide the treatment ladder.
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MRI is gold standard
Modern cartilage-sensitive MRI (T2 mapping, dGEMRIC) shows lesion size, depth and subchondral bone oedema before any surgery is planned.
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Treatable
A stepped plan from conservative care to biological cartilage repair and, where needed, realignment surgery restores function for most patients.
Why this guide matters
A stepped ladder, not a single operation.
Cartilage repair is one of the fastest-moving areas of orthopaedic surgery. The three points below shape everything on this page.
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Cartilage does not heal itself
Articular cartilage has no blood supply. Left alone, focal defects can enlarge and drive early osteoarthritis. Early, correct diagnosis matters.
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The right operation for the right lesion
Small defects, mid-sized biological repairs and larger allografts each have a place. Age, alignment and meniscal status guide the choice.
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Rehab is half the operation
Protected weight bearing, structured physio and a graded return to sport at six to nine months protect the repair.
How the diagnosis is made
From first twist to a clear cartilage plan.
The steps a UK sports orthopaedic surgeon will normally follow, in order, so you know what to expect and why.
Phase 1 · Assessing
Mechanism, exam and weight-bearing X-ray
Phase 2 · Confirming
Cartilage MRI and alignment views
Phase 3 · Planning
Arthroscopy and MDT decision
- 01
Assessing
Clinical history and mechanism
Was there a specific twist, dislocation or direct blow, or has the joint grumbled for months? Locking, catching and giving way point to a mechanical cartilage lesion.
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Assessing
Joint examination
Effusion, joint line tenderness, range of movement and joint-specific tests (McMurray, patellar grind, ankle impingement, hip FADIR) localise the problem.
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Assessing
Weight-bearing X-ray
Standing views of the affected joint look for joint space narrowing, loose osteochondral fragments and early osteoarthritis.
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Confirming
Cartilage-sensitive MRI
The gold standard investigation. T2 mapping and dGEMRIC sequences assess cartilage composition and subchondral bone marrow oedema.
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Confirming
Long-leg alignment views
For knee lesions a full-length standing X-ray checks for varus or valgus malalignment that would overload any repair.
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Planning
Diagnostic arthroscopy
Direct visualisation with a probe remains the reference standard for grading and mapping the lesion, and is often combined with a repair procedure.
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Planning
MDT cartilage discussion
Specialist cartilage centres discuss age, activity level, defect size, alignment and meniscal status to choose the right technique.
Typical timeline: a first specialist visit to a defined plan in weeks, not months.
Symptoms
What a chondral injury actually feels like.
The classic mix of mechanical symptoms, focal pain and swelling, and the features that mean it is time to escalate.
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Mechanical locking
A loose cartilage or osteochondral fragment can wedge in the joint and stop movement briefly.
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Catching and clicking
Painful catching on certain movements often reflects a chondral flap or unstable lesion.
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Giving way
The joint feels unreliable, especially on stairs, twisting or uneven ground.
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Recurrent effusion
A swollen joint that puffs up after activity is a common early sign of cartilage injury.
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Focal, activity-related pain
Pain sits over one part of the joint line and worsens with impact or deep flexion.
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Post-injury stiffness
Weeks or months after a twist or dislocation the joint stays sore and stiff rather than settling.
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Silent lesions
Some chondral defects are found incidentally on MRI. Whether to treat depends on symptoms, size and site.
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Red flag - true locked joint
A joint stuck in flexion with a hard block needs urgent orthopaedic review to exclude a displaced fragment.
Treatment
How chondral injury is treated in the UK.
Conservative care first. Biological cartilage repair for symptomatic focal defects in younger active patients. Alignment surgery and, at end stage, joint replacement.
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Activity modification and physio
Load management, quadriceps and hip strengthening, gait retraining and bracing form the base of every plan.
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NSAIDs and weight optimisation
Short-course anti-inflammatories and, where relevant, weight loss reduce joint load and pain.
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Intra-articular injection
Steroid, hyaluronic acid or PRP injections can settle symptoms and buy time before surgical decisions.
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Microfracture and drilling
Small (under 2 cm squared) defects. Creates a fibrocartilage repair. Use is declining in favour of biological techniques.
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Autologous chondrocyte implantation
ACI or MACI (matrix-induced). A two-stage biological repair best suited to lesions of 2 to 8 cm squared in younger active patients.
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Osteochondral autograft (OATS)
Mosaicplasty. Cylindrical plugs of bone and cartilage are transplanted from a low-load area to the defect.
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Osteochondral allograft
For larger defects or where previous surgery has failed. Donor bone and cartilage restores the joint surface.
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Minced cartilage and scaffolds
Newer options including Chondro-Gide, Cartistem, Novocart 3D and Agili-C use biological scaffolds to support cartilage regrowth.
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Subchondroplasty
Calcium phosphate injected under the defect treats painful subchondral bone marrow oedema alongside cartilage repair.
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Realignment osteotomy
High tibial (HTO) or distal femoral (DFO) osteotomy unloads a repaired compartment and is often done at the same sitting.
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Meniscal preservation or transplant
Repairing or, rarely, transplanting the meniscus protects any cartilage repair from repeat failure.
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Partial or total joint replacement
For end-stage joint damage where biological repair is no longer feasible.
See our related treatment guides on cartilage restoration and repair, autologous chondrocyte implantation (MACI), osteotomy realignment surgery and, at end stage, total knee replacement.
What this guide is based on
The sources behind every claim on this page.
UK national guidance and specialist society standards, current at the time of last review.
Key references
Guidelines and standards we relied on.
A quiet reminder
This guide is for information, not medical advice.
Your orthopaedic surgeon and physiotherapist know your joint, your imaging and your goals. They can tell you which parts apply to you.
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British Association for Surgery of the Knee (BASK). Cartilage repair consensus statements.
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British Orthopaedic Association (BOA). Standards for cartilage restoration and knee surgery.
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International Cartilage Regeneration and Joint Preservation Society (ICRS). Classification and treatment recommendations.
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NICE. Interventional procedures guidance on autologous chondrocyte implantation (TA477) and matrix-induced cartilage repair.
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European Society for Sports Traumatology, Knee Surgery and Arthroscopy (ESSKA). Cartilage and osteotomy consensus.
Red flags
When a chondral injury needs urgent attention.
Most chondral injuries can be worked up in the clinic. These are the situations where a specialist opinion is needed now.
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True locked joint
A knee or ankle stuck in flexion with a hard mechanical block needs urgent orthopaedic review to exclude a displaced osteochondral fragment.
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Acute large effusion after trauma
A tense, painful swollen joint within hours of injury can mean a haemarthrosis from a significant osteochondral fracture.
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Osteochondritis dissecans in a child
Bone and cartilage fragment separation in children or adolescents (knee, elbow, talus) needs early paediatric orthopaedic input.
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Loose body symptoms
Recurrent locking, catching or a palpable moving lump inside the joint suggests a loose fragment that needs removal or fixation.
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Rapidly progressive pain and swelling
Escalating rest pain, night pain or systemic symptoms need urgent review to exclude infection, avascular necrosis or tumour.
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Failed prior cartilage surgery
Ongoing symptoms after microfracture, ACI or osteotomy warrant referral to a specialist cartilage centre for revision options.
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Sudden inability to weight bear
A joint that will no longer take weight after a twisting injury needs prompt imaging and orthopaedic assessment.
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Fixed deformity
A new varus or valgus deformity in a symptomatic joint changes surgical planning and should be flagged early.
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Suspected infection
Hot, red, systemically unwell joint after any injection or surgery is a septic joint until proven otherwise.
Living with it
A treatable injury, with a clear rehab ladder.
Four things that make the biggest difference after cartilage surgery. Respect the timeline, do the rehab, fix the mechanics, and think in years not weeks.
A quiet reminder
Cartilage rewards patience.
A repair that is loaded too soon can fail. Weeks of protected rehab now protect the joint for years.
- 01 Load
Respect the healing timeline
Cartilage repairs are slow. Expect protected weight bearing for around six weeks and a graded return to sport at six to nine months.
- 02 Rehab
Specialist cartilage rehab
Structured physio, continuous passive motion where indicated and progressive loading are as important as the surgery itself.
- 03 Alignment
Fix the underlying mechanics
A repair placed into a malaligned joint will fail. Address alignment, meniscal loss and instability at the same time.
- 04 Longevity
Play the long game
The aim is to delay or prevent osteoarthritis. Weight, strength and activity choices over years matter as much as the operation itself.
Frequently asked
Everything we get asked about chondral injury.
Quick answers on grading, imaging, cartilage repair techniques and rehab.
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What is a chondral injury?
A chondral injury is a focal defect in the articular cartilage that lines a joint. It can be caused by a specific twist, blow or dislocation, or develop over time from malalignment, meniscal loss or previous injury. The knee is by far the most common site.
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How is a chondral injury different from arthritis?
Osteoarthritis is diffuse wear across the whole joint surface. A chondral injury is a focal, well-defined defect that can often be repaired biologically. Untreated chondral defects can, over time, contribute to osteoarthritis. See our related guide on cartilage injury for the broader picture.
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What is the Outerbridge classification?
Outerbridge grades chondral damage from I to IV. Grade I is softening of the cartilage. Grade II is fissuring under 1.5 cm. Grade III is fissuring over 1.5 cm reaching the subchondral bone. Grade IV is full-thickness cartilage loss with exposed bone. The ICRS 0 to 4 system is used similarly in specialist practice.
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What is osteochondritis dissecans (OCD)?
OCD is a separate but related condition where a fragment of bone and its overlying cartilage separates from the joint surface. It classically affects children and adolescents in the knee, elbow or talus and needs early specialist assessment because the fragment can loosen and become a loose body.
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Do I always need surgery?
No. Many chondral injuries settle with conservative care - activity modification, physiotherapy, weight optimisation and, where appropriate, intra-articular injection. Surgery is considered for symptomatic focal defects in younger, active patients, or for loose bodies, mechanical locking and failed conservative care.
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Which cartilage repair technique is right for me?
It depends on the size and site of the defect, your age and activity level, joint alignment and meniscal status. Small defects may suit minced cartilage or microfracture. Mid-sized defects of 2 to 8 cm squared often suit MACI. Larger defects may need osteochondral allograft, with realignment osteotomy if the joint is unbalanced. A specialist cartilage MDT will guide the choice.
Related content
Keep reading.
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Cartilage injury
The broader hub across joints and grades.
Learn more -
Arthritis
The long-term consequence of untreated cartilage loss.
Learn more -
Avascular necrosis
Loss of blood supply that damages joint bone and cartilage.
Learn more -
Calcium crystal diseases
Crystal-driven joint damage and cartilage calcification.
Learn more -
Meniscal tear
Meniscal loss changes the load on knee cartilage.
Learn more -
Cartilage restoration and repair
The modern surgical ladder in detail.
Learn more -
Autologous chondrocyte implantation
MACI and two-stage biological cartilage repair.
Learn more -
Osteotomy realignment surgery
HTO and DFO to unload a repaired compartment.
Learn more -
Total knee replacement
When biological repair is no longer feasible.
Learn more -
Arthroscopic knee surgery
Keyhole diagnosis, mapping and treatment.
Learn more -
Cortisone injection (large joint)
Targeted anti-inflammatory injection.
Learn more -
Private MRI scan
Cartilage-sensitive imaging - the gold standard.
Learn more -
Private CT scan
Detailed bone imaging for osteochondral lesions.
Learn more