Health condition · Clinically reviewed
Food poisoning, the UK picture, the red flags - and when antibiotics belong.
Two million cases a year, most self-limiting - but the small minority that isn’t needs the right pathway, quickly. Here is what to look for and what to do.
Why trust this guide
- 01
Clinically reviewed
Written by our editorial team and reviewed by a registered UK clinician before publication.
- 02
Sourced from guidance
Checked against NICE, UKHSA and Food Standards Agency guidance you can see at the end.
- 03
Current for 2026
Reflects modern UK guidance including notification duties, STEC/O157 antibiotic warnings and outbreak response.
Key facts
Food poisoning at a glance.
The essentials, in plain English - the scale of it, the usual culprits and how it is treated in the UK today.
-
What it is
Foodborne illness caused by bacteria, viruses, parasites or preformed toxins in contaminated food or water.
-
How common
The UK sees roughly 2.4 million cases a year - most are self-limiting and never reach the health service.
-
Top UK bacteria
Campylobacter (chicken) and Salmonella (poultry and eggs) lead the notifiable list, with Listeria carrying the highest mortality.
-
Top UK virus
Norovirus is the single biggest cause of viral gastroenteritis and closed-setting outbreaks.
-
Backbone treatment
Oral rehydration with Dioralyte or WHO ORS - antibiotics are reserved for specific pathogens, not routine care.
-
Notification duty
Suspected food poisoning is a UKHSA-notifiable condition - clinicians report suspected cases, not just confirmed ones.
Why this guide matters
The pathway, not just the pathogens.
Most cases settle. The value of a good guide is in spotting the ones that won’t - and knowing exactly what to do next.
-
Rehydration is the treatment
Oral rehydration solution, in small frequent sips, is the mainstay - not a broth of antibiotics. IV fluids are for severe dehydration only.
-
STEC O157 is the exception
Bloody diarrhoea with recent burger, unpasteurised dairy or petting-farm exposure raises the risk of haemolytic uraemic syndrome. Loperamide and antibiotics are avoided.
-
Public health is part of care
Suspected food poisoning is notifiable to UKHSA before culture confirmation - it starts outbreak control while the patient is being treated.
How the diagnosis is made
From first symptom to a clear plan.
The steps a UK GP, A&E clinician or infectious diseases team will normally follow - so you know what to expect and why.
Phase 1 · Assessing
History, hydration and red-flag screen
Phase 2 · Confirming
Stool and blood investigations
Phase 3 · Acting
Notification and specialist input
- 01
Assessing
Focused history
Timing of onset, foods eaten, travel, occupation, household contacts, pregnancy status and risk group - the story usually points at the pathogen.
- 02
Assessing
Hydration and vitals check
Pulse, blood pressure, capillary refill, mucous membranes and mental state - the pivotal call is whether oral rehydration will do or IV fluids are needed.
- 03
Assessing
Red-flag screen
Bloody diarrhoea, high fever, reduced consciousness, pregnancy, immunocompromise and extremes of age all change the pathway.
- 04
Confirming
Stool testing
Stool culture, multiplex PCR panel, ova-cyst-parasite microscopy and selective C. difficile testing when the picture fits.
- 05
Confirming
Bloods when systemic
FBC, U&Es, LFTs, CRP, coagulation and LDH - LDH and a fragmented film help flag haemolytic uraemic syndrome after STEC O157.
- 06
Acting
Notify UKHSA
Suspected food poisoning and specific pathogens are statutorily notifiable - the form goes in before culture confirmation.
- 07
Acting
Specialist input
Infectious diseases, tropical medicine or gastroenterology - for travellers, immunocompromise, persistent symptoms or suspected outbreak.
Typical timeline: first assessment to a settled plan within one visit for most patients.
Symptoms
What food poisoning actually feels like.
The classic mix of nausea, vomiting, diarrhoea and cramp - plus the features that suggest something more than a routine bug.
-
Nausea and vomiting
Often the first feature - very short onset (1 to 6 hours) points at a preformed toxin such as Staph aureus or Bacillus cereus.
-
Watery diarrhoea
The commonest picture - norovirus, Salmonella and enterotoxigenic E. coli all sit here.
-
Bloody diarrhoea
Suggests invasive or Shiga-toxin bacteria - Shigella, Campylobacter or STEC O157. Antibiotics and loperamide are avoided in suspected STEC.
-
Abdominal cramps
Often severe with invasive pathogens - Campylobacter cramps can mimic appendicitis.
-
Fever and systemic upset
Suggests invasive disease - Salmonella, Shigella, Listeria or typhoid deserve blood cultures.
-
Dehydration
Dry mucous membranes, thirst, reduced urine, dizziness on standing - the main risk in the first 48 hours.
-
Descending paralysis
Blurred vision, dysphagia and weakness after home-canned food - suspect botulism and treat as an emergency.
-
Red flag - bloody stool or HUS signs
Bloody stool with pallor, bruising or reduced urine after burger or contaminated produce points at STEC O157 and possible haemolytic uraemic syndrome.
Treatment
How food poisoning is treated in the UK.
Rehydration is the backbone. Antiemetics keep it going. Antibiotics are targeted, not routine - and public health action is part of care, not an extra.
-
Oral rehydration
Dioralyte or WHO ORS in small, frequent sips - the backbone for almost every mild-to-moderate case.
-
IV fluids and admission
For severe dehydration, persistent vomiting, reduced consciousness or high-risk groups who cannot keep fluids down.
-
Antiemetic
Ondansetron, prochlorperazine or metoclopramide - selective use to keep oral rehydration going.
-
Antidiarrhoeal (loperamide)
Useful in adult watery diarrhoea - avoided in bloody diarrhoea, suspected STEC, C. difficile and children under 6.
-
Targeted antibiotics
Reserved for specific pathogens - azithromycin for Campylobacter, metronidazole for Giardia, ceftriaxone for typhoid. Not for STEC O157.
-
Botulinum antitoxin
Specialist commissioned - given with supportive care and airway monitoring alongside urgent UKHSA notification.
-
Pregnancy pathway
Listeria and Toxoplasma need obstetric and infectious diseases input - antenatal monitoring and pathogen-specific treatment.
-
Public health action
UKHSA notification, local authority environmental health investigation and outbreak control - part of care, not an extra.
What this guide is based on
The sources behind every claim on this page.
UK national guidance and specialist agency standards, current at the time of last review.
Key references
Guidelines and standards we relied on.
A quiet reminder
This guide is for information, not medical advice.
Your GP, A&E clinician or infectious diseases team knows your history and can tell you which parts apply to you. If in doubt, get seen.
-
NICE CKS. Gastroenteritis.
-
UK Health Security Agency. Notifiable diseases and causative organisms: how to report.
-
UKHSA. Guidance on the management of Shiga toxin-producing E. coli (STEC).
-
Food Standards Agency. Foodborne illness in the UK - annual report.
Red flags
When food poisoning needs urgent attention.
Most cases are safely managed at home. These are the situations that aren’t - and where a specialist opinion or urgent admission is needed.
-
Bloody diarrhoea
Suspect STEC O157 or invasive bacteria. Do not give antibiotics or loperamide until STEC is excluded - both raise the risk of haemolytic uraemic syndrome.
-
Haemolytic uraemic syndrome
Pallor, bruising, reduced urine or confusion 5 to 10 days after bloody diarrhoea - admit and check FBC, film, U&Es and LDH urgently.
-
Severe dehydration
Reduced consciousness, hypotension, minimal urine output - needs IV fluids and admission, not another sachet of ORS.
-
Pregnancy
Listeria, Toxoplasma and hepatitis E all carry fetal and maternal risk - low threshold for obstetric and infectious diseases review.
-
Immunocompromise
Chemotherapy, transplant, HIV or biologic therapy - lower threshold for admission, blood cultures and pathogen-specific antibiotics.
-
Suspected botulism
Blurred vision, dysphagia and descending weakness after canned or fermented food - immediate hospital care and UKHSA notification.
-
Traveller with fever
Fever plus diarrhoea after travel - consider typhoid, invasive Salmonella, amoebiasis and malaria alongside the usual causes.
-
Guillain-Barré after Campylobacter
Ascending weakness and areflexia 1 to 3 weeks after Campylobacter - a neurology emergency needing admission.
-
Reactive arthritis
Joint pain, urethritis and conjunctivitis after Salmonella, Shigella, Campylobacter or Yersinia - rheumatology referral.
Living with it
A short illness, with a clear pathway.
Four things that make the biggest difference day to day - fluids in, food back in early, breaking the chain of transmission, and preventing the next one.
A quiet reminder
Small sips, often - and no cooking for others until 48 hours clear.
The two simplest habits stop most complications and stop most household outbreaks.
- 01 Fluids
Little and often
Small sips of oral rehydration solution beat big glasses of water - and beat sports drinks, which are too sugary.
- 02 Food
Eat when you can
Return to a normal diet as soon as it is tolerated - starvation slows recovery. Bland foods first, then normal food.
- 03 Hygiene
Break the chain
Thorough handwashing with soap and water, no food preparation while symptomatic, and 48 hours symptom-free before going back to work, school or nursery.
- 04 Prevent
Cook, chill, separate, clean
Cook meat and eggs thoroughly, chill leftovers within two hours, keep raw and cooked separate, and wash produce - the four rules that stop most cases.
Frequently asked
Everything we get asked about food poisoning.
Quick answers on rehydration, antibiotics, when to go to A&E and how to prevent the next one.
-
What is food poisoning?
A short illness caused by eating or drinking something contaminated with bacteria, viruses, parasites or preformed toxins. In the UK, Campylobacter, Salmonella and norovirus are the biggest causes - most cases settle in 24 to 72 hours with rest and fluids.
-
How do I tell viral from bacterial food poisoning?
Timing and symptoms give clues. Very short onset (1 to 6 hours) with prominent vomiting points at a preformed bacterial toxin. Longer onset (over 12 hours) with fever and blood in the stool suggests invasive bacteria. Norovirus classically causes a shorter illness with more vomiting and less blood. Only stool testing confirms the pathogen.
-
Should I take antibiotics for food poisoning?
Usually no. Most cases are self-limiting and antibiotics are reserved for specific pathogens - Campylobacter (azithromycin), Giardia (metronidazole), typhoid (ciprofloxacin or ceftriaxone) and a few others. In suspected STEC O157, antibiotics are actively avoided because they raise the risk of haemolytic uraemic syndrome.
-
When should I go to A&E?
Go urgently for signs of severe dehydration, bloody diarrhoea, high fever with confusion, descending paralysis, or if you are pregnant, immunocompromised or at the extremes of age. Prolonged vomiting that stops you keeping any fluid down is another reason to be seen.
-
Is food poisoning notifiable in the UK?
Yes. Suspected food poisoning is a statutorily notifiable condition and clinicians report it to UKHSA before culture confirmation. Specific organisms - Salmonella, Shigella, Listeria, STEC, cholera, typhoid, botulism and others - are separately notifiable when identified in the laboratory.
-
How do I prevent food poisoning at home?
The Food Standards Agency four rules cover most cases - cook food thoroughly (especially poultry, mince and eggs), chill leftovers within two hours, keep raw and cooked food separate, and clean hands, surfaces and utensils. In pregnancy, avoid unpasteurised dairy, soft cheeses, pâté, deli meats and undercooked meat.
Related content
Keep reading.
-
Diarrhoea
Understanding acute and chronic diarrhoea.
Learn more -
Dehydration
The main risk from any gut infection.
Learn more -
E. coli
STEC O157 and the HUS pathway.
Learn more -
Chronic diarrhoea
When symptoms outlast the usual 72 hours.
Learn more -
Haemolytic uraemic syndrome
The serious complication of STEC O157.
Learn more -
Colonoscopy
Related diagnostic test and treatment option.
Learn more -
Faecal microbiota transplant
For refractory C. difficile after antibiotics.
Learn more -
Gut microbiome testing
Related diagnostic test.
Learn more -
Private childhood vaccinations
Rotavirus, hepatitis A and travel cover.
Learn more -
All conditions
Browse every clinical guide.
Learn more