Health condition · Clinically reviewed
GORD, lifestyle, acid suppression - and when surgery earns its place.
One in five UK adults get troublesome reflux every week. Most is managed well with lifestyle change and a short course of a proton pump inhibitor. Some needs endoscopy, and a few benefit from an operation.
Why trust this guide
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Clinically reviewed
Written by our editorial team and reviewed by a registered UK clinician before publication.
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Sourced from guidance
Cross-checked against NICE CG184, NG12 and British Society of Gastroenterology sources.
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Current for 2026
Reflects UK guidance on PPI stewardship, endoscopy access and modern antireflux surgery.
Key facts
GORD at a glance.
The essentials, in plain English. What it is, who gets it, what UK guidance recommends, and when to seek urgent review.
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What it is
Retrograde flow of stomach contents into the oesophagus causing troublesome symptoms or mucosal damage.
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How common
Around one in five UK adults experience troublesome reflux symptoms at least weekly.
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Types
Erosive oesophagitis, non-erosive reflux disease (NERD), Barrett oesophagus and extra-oesophageal reflux.
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Key drivers
Obesity, hiatus hernia, pregnancy, smoking, alcohol and certain medications including NSAIDs and calcium channel blockers.
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Foundation therapy
Lifestyle change plus a proton pump inhibitor at full dose for four to eight weeks, then a step-down plan.
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When to escalate
Dysphagia, weight loss, GI bleeding, anaemia, or new symptoms over age 55 need urgent upper GI endoscopy per NICE NG12.
Why this guide matters
A stepped plan, not a lifetime of tablets.
GORD is common and usually manageable. The three points below shape everything else on this page.
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Lifestyle is not a footnote
Weight loss, meal timing and raising the head of the bed measurably reduce reflux and can lower or remove the need for medication.
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PPIs are a treatment, not a habit
A full-dose course for four to eight weeks, then a step-down. Long-term daily use needs a clear indication and review.
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Endoscopy answers the hard questions
For alarm features, refractory symptoms or before surgery, upper GI endoscopy and pH-impedance testing change the plan.
How the diagnosis is made
From first symptoms to a clear plan.
The steps a UK GP or gastroenterologist will normally follow, in order, so you know what to expect and why.
Phase 1 · Assessing
History, red flags and empirical trial
Phase 2 · Confirming
Endoscopy, pH-impedance and manometry
Phase 3 · Planning
Specialist MDT and long-term plan
- 01
Assessing
History and red-flag screen
A careful review of heartburn, regurgitation, cough and any alarm features that would trigger a two-week wait referral.
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Assessing
Empirical trial of PPI
For typical symptoms without red flags, a full-dose PPI for four to eight weeks is both treatment and a diagnostic clue.
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Assessing
Helicobacter pylori test
Test-and-treat is considered in refractory dyspepsia and in patients requiring long-term acid suppression.
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Confirming
Upper GI endoscopy (OGD)
Indicated for red flags, refractory symptoms, Barrett surveillance or before antireflux surgery. See our gastroscopy guide.
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Confirming
Ambulatory 24-hour pH-impedance
The gold standard for confirming acid and non-acid reflux, and for correlating symptoms with reflux events.
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Confirming
High-resolution manometry
Selective use to exclude motility disorders such as achalasia before surgery or when swallowing is disordered.
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Planning
Specialist MDT review
Refractory, complicated or surgical candidates are reviewed by gastroenterology and upper GI surgery together.
Typical timeline: first visit to a settled plan in weeks, endoscopy where indicated within a few weeks more.
Symptoms
What GORD actually feels like.
Classic heartburn and regurgitation, plus the throat, chest and dental clues that reflux is behind less obvious symptoms - and the features that mean it is time to escalate.
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Heartburn
A burning retrosternal discomfort, worse after meals and when lying down or bending forwards.
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Regurgitation
Effortless return of gastric contents into the mouth or throat, often with a sour or bitter taste.
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Water brash
A sudden flood of saliva in response to reflux, sometimes mistaken for excess mucus.
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Chest pain
Non-cardiac chest pain from reflux can mimic angina. Cardiac causes must be excluded first.
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Dysphagia
Difficulty swallowing can signal stricture, severe oesophagitis or malignancy. See our dysphagia guide.
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Chronic cough and hoarseness
Extra-oesophageal reflux can cause a long-standing cough, throat clearing and a rough voice.
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Dental erosion and halitosis
Acidic reflux thins tooth enamel and drives unexplained bad breath, particularly on waking.
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Red flag - dysphagia or weight loss
New dysphagia, weight loss, bleeding, anaemia or symptoms over age 55 warrant urgent upper GI endoscopy.
Treatment
How GORD is treated in the UK.
Lifestyle first, PPI therapy as the backbone, endoscopy where indicated, and antireflux surgery for the minority who need it.
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Lifestyle and weight
Weight loss, raising the head of the bed, smaller evening meals and avoiding late-night eating make a measurable difference.
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Proton pump inhibitor
Omeprazole, lansoprazole, pantoprazole, esomeprazole or rabeprazole at full dose for four to eight weeks, then step-down.
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H2 receptor antagonist
Famotidine is a useful second-line or add-on option, especially for nocturnal breakthrough symptoms.
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Alginates and antacids
Gaviscon-style alginates form a raft on the gastric contents and give quick, on-demand relief.
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Prokinetic (selective)
Metoclopramide or domperidone can help in selected cases, with MHRA-guided time limits and monitoring.
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Laparoscopic fundoplication
Nissen or Toupet fundoplication remains the gold-standard antireflux operation for refractory or PPI-intolerant disease.
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LINX and endoscopic options
LINX magnetic sphincter augmentation, Stretta radiofrequency and TIF are alternatives in carefully selected patients.
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Barrett surveillance and RFA
Endoscopic surveillance, radiofrequency ablation, EMR or ESD for dysplastic Barrett oesophagus in a specialist unit.
What this guide is based on
The sources behind every claim on this page.
UK national guidance and specialist society standards, current at the time of last review.
Key references
Guidelines and standards we relied on.
A quiet reminder
This guide is for information, not medical advice.
Your GP or gastroenterologist knows your history and can tell you which parts apply to you. If in doubt, get seen.
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NICE CG184. Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management.
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NICE NG12. Suspected cancer: recognition and referral (upper GI cancer criteria).
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British Society of Gastroenterology. Guidelines on oesophageal manometry, pH-impedance and Barrett oesophagus.
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MHRA. Drug safety updates on metoclopramide, domperidone and long-term PPI use.
Red flags
When reflux needs urgent attention.
Most GORD is manageable in primary care. These are the situations that are not, and where NICE NG12 or specialist input is needed.
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Dysphagia
New or progressive difficulty swallowing needs urgent upper GI endoscopy on a two-week-wait pathway.
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Unintentional weight loss
Weight loss with reflux symptoms is a NICE NG12 alarm feature and mandates urgent specialist review.
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Gastrointestinal bleeding
Haematemesis, coffee-ground vomiting or melaena is an emergency requiring same-day assessment.
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Iron-deficiency anaemia
Unexplained anaemia in a patient with reflux warrants both upper GI and lower GI investigation.
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New symptoms over age 55
Fresh dyspepsia or reflux over age 55, especially if persistent, meets criteria for urgent endoscopy.
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Cardiac chest pain
Reflux can mimic angina. Any cardiac features need urgent cardiology assessment first.
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Refractory symptoms on high-dose PPI
Ongoing symptoms despite optimised PPI therapy deserve endoscopy and ambulatory pH-impedance testing.
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Barrett oesophagus with dysplasia
High-grade dysplasia or early adenocarcinoma is treated in a specialist upper GI centre with RFA, EMR or surgery.
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Aspiration and pulmonary symptoms
Recurrent aspiration, pneumonia or worsening asthma related to reflux needs joint respiratory and GI input.
Living with it
A treatable condition, with a clear ladder.
Four things that make the biggest difference day to day: weight and posture, meal timing, knowing your personal triggers, and refusing to drift on long-term medication without a review.
A quiet reminder
Consistency beats intensity, every time.
Small, steady habits kept up for months do more than a heroic week that does not last.
- 01 Routine
Weight and posture win
Modest weight loss and raising the head of the bed by 15 to 20 centimetres reduce night-time reflux more than any diet change.
- 02 Timing
Give the stomach three hours
Finishing meals at least three hours before lying down prevents most nocturnal breakthrough symptoms.
- 03 Triggers
Find your personal list
Alcohol, coffee, chocolate, spicy food, tomatoes and citrus affect people differently. Track what actually matters for you.
- 04 Escalate
Don’t drift on long-term PPIs
If you need daily acid suppression for months, revisit the diagnosis, review medication and consider endoscopy or surgery.
Frequently asked
Everything we get asked about GORD.
Quick answers on PPIs, endoscopy, Barrett oesophagus and antireflux surgery.
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What is gastro-oesophageal reflux disease (GORD)?
GORD is the retrograde flow of stomach contents into the oesophagus in a way that causes troublesome symptoms or mucosal complications. It ranges from non-erosive reflux disease with a normal endoscopy through erosive oesophagitis to Barrett oesophagus and, rarely, oesophageal adenocarcinoma.
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When should I see a doctor about heartburn?
See a clinician if reflux is frequent, wakes you at night, needs regular over-the-counter treatment or fails to settle after a four-to-eight-week PPI trial. Seek urgent review for dysphagia, weight loss, bleeding, anaemia or new symptoms over age 55.
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Do I need an endoscopy?
Not everyone. Typical symptoms without red flags are usually managed empirically. Upper GI endoscopy is offered for alarm features, refractory disease, Barrett surveillance and before antireflux surgery. Our gastroscopy guide explains what to expect.
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How long should I stay on a proton pump inhibitor?
NICE recommends a full-dose PPI for four to eight weeks, then a step-down to the lowest effective dose or on-demand use. Long-term daily PPIs are appropriate for erosive oesophagitis, Barrett oesophagus and after complications, with periodic review.
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Are proton pump inhibitors safe long-term?
For most patients the balance of benefit is favourable, but long-term use has been associated with small increases in fracture risk, kidney disease, hypomagnesaemia and Clostridioides difficile infection. Regular review, the lowest effective dose and a clear indication are the pillars of safe long-term prescribing.
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When is surgery for reflux appropriate?
Antireflux surgery, most commonly laparoscopic Nissen or Toupet fundoplication, is considered for refractory symptoms, PPI intolerance, large hiatus hernia or a strong patient preference to avoid lifelong medication. LINX and endoscopic options such as Stretta or TIF are alternatives in selected cases.
Related content
Keep reading.
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Dyspepsia
Upper-abdominal discomfort and its overlap with reflux.
Learn more -
Functional dyspepsia
When symptoms persist with a normal endoscopy.
Learn more -
Oesophagitis
Inflammation of the oesophageal lining.
Learn more -
Oesophageal cancer
A rare but important reflux-related complication.
Learn more -
Dysphagia
Difficulty swallowing - always investigate promptly.
Learn more -
Gastroscopy
Upper GI endoscopy explained.
Learn more -
Laparoscopic Nissen fundoplication
Gold-standard antireflux surgery.
Learn more -
LINX magnetic sphincter
A device-based alternative to fundoplication.
Learn more -
RFA for Barrett oesophagus
Endoscopic ablation of dysplastic Barrett.
Learn more -
24-hour pH-impedance monitoring
The gold-standard reflux test.
Learn more -
Colonoscopy
Lower GI endoscopy where anaemia or bleeding needs review.
Learn more -
Gut microbiome testing
Emerging insight into the gut in reflux and dyspepsia.
Learn more