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Patient guide · Reproductive medicine and embryology

Time-lapse imaging (embryology), continuous embryo observation for smarter IVF embryo selection.

Time-lapse imaging (EmbryoScope, Geri, MIRI) watches embryos continuously during IVF. Embryologists pick embryos on how they actually develop hour by hour, rather than on a snapshot taken once a day.

Read the key facts
Time-lapse embryo imaging inside a specialist IVF incubator

Why patients choose us

  • 01

    The right hands

    We route you to a consultant embryologist working with time-lapse — the person choosing your embryos decides the answer.

  • 02

    Continuous, undisturbed

    Embryos stay inside the incubator throughout the culture period, with imaging every 5–20 minutes.

  • 03

    Independent, and free

    We are paid by no clinic, so the recommendation is impartial and costs you nothing.

Key facts

What time-lapse imaging actually does.

Time-lapse imaging captures every stage of embryo development without disturbing the culture environment — turning selection into a data-rich decision.

  • Definition

    Embryos are monitored continuously in a specialist incubator with a built-in microscope camera.

  • Specialist time-lapse incubator

    Systems such as EmbryoScope, Geri and MIRI provide a stable, uninterrupted culture environment.

  • No embryo disturbance

    Embryos remain in a controlled environment — no removal for daily microscopic checks.

  • Morphokinetic analysis

    Precise timing of every developmental event, from first cleavage to blastocyst expansion.

  • KIDScore algorithms

    Validated scoring algorithms rank embryos on their kinetics to support selection.

  • Complements PGT and morphological grading

    Time-lapse adds a kinetic dimension — it does not replace preimplantation genetic testing or standard grading.

The problem

Embryo selection is only as good as the observation window.

Traditional culture checks are fixed daily snapshots. Time-lapse captures the events between them — where the useful information often is.

  • Recurrent implantation failure?

    Kinetic data can surface patterns missed on daily assessment and shape a revised transfer plan.

  • Multiple good-grade embryos?

    Where morphology alone can’t rank them, morphokinetic scoring provides a defensible tiebreaker.

  • Considering blastocyst transfer?

    Continuous monitoring supports safe extended culture and precise selection at day 5–6.

Preparation and pathway

From consultation to plan — what happens, in order.

One embryology team, from oocyte retrieval through morphokinetic analysis to selected transfer.

  1. 01

    Before

    Fertility consultation

    Detailed history and investigations set out whether time-lapse is likely to add value in your IVF cycle.

  2. 02

    Before

    Egg retrieval and ICSI

    Standard IVF pathway — controlled ovarian stimulation, oocyte retrieval and insemination or ICSI as planned.

  3. 03

    Laboratory

    Embryos placed in the incubator

    Fertilised embryos are loaded into a dedicated well within the time-lapse incubator, undisturbed for the culture period.

  4. 04

    Laboratory

    Continuous imaging over 5–6 days

    Images are captured every 5–20 minutes across multiple focal planes, producing a full developmental record.

  5. 05

    Laboratory

    Morphokinetic analysis

    Embryologists review timing of pronuclear appearance, cleavage divisions, compaction and blastulation.

  6. 06

    After

    Embryo selection

    The best-scoring embryo — combining morphology, kinetics and any PGT results — is chosen for transfer.

  7. 07

    After

    Structured plan

    Transfer plan, remaining embryos frozen where suitable, and a written summary for your onward fertility team.

Typical culture window: 5–6 days of continuous imaging, then selection and transfer plan.

What it shows

What time-lapse imaging can — and can’t — answer.

Morphokinetic data enriches selection between viable-looking embryos. It does not replace genetic testing or good clinical judgement.

  • Time to first cleavage

    Early cleavage timing is a well-recognised marker of embryo developmental potential.

  • Time to blastocyst

    Duration to blastulation is captured precisely, not inferred from a single daily snapshot.

  • Cell-cycle synchrony

    Synchronous divisions correlate with viability; asynchrony is quantified rather than estimated.

  • Multinucleation events

    Multinucleation at the 2- and 4-cell stage — often missed on static checks — is reliably detected.

  • Direct cleavage abnormality

    Direct 1-to-3 cell divisions, invisible on daily microscopy, are flagged and factored into selection.

  • Fragmentation dynamics

    Fragmentation is tracked over time, including reabsorption — not a single fixed snapshot.

  • Blastocyst expansion

    Expansion, contraction cycles and hatching are recorded and used to grade viability.

  • Red flag: abnormal cleavage — deselect

    Embryos with direct cleavage or severe multinucleation are typically deselected for transfer.

Treatment options

Turning selection into a treatment plan.

What can — and should — happen once the morphokinetic analysis is complete.

  • Fresh embryo transfer

    Transfer of the highest-ranked embryo within the same cycle where the endometrium is receptive.

  • Frozen embryo transfer

    Vitrification of selected embryos for a later, hormonally optimised transfer cycle.

  • Blastocyst culture

    Extended culture to day 5–6 to allow morphokinetic selection at the blastocyst stage.

  • Assisted hatching

    Laser thinning of the zona pellucida where indicated by embryo characteristics or history.

  • PGT-A / PGT-M

    Preimplantation genetic testing for aneuploidy or a monogenic disorder, combined with time-lapse selection.

  • Endometrial receptivity analysis

    Testing to identify the personalised window of implantation for a subsequent transfer.

  • Fertility follow-up

    Structured follow-up with your consultant to plan next steps after outcome — positive or negative.

  • MDT review

    Multidisciplinary review with reproductive medicine, embryology and genetics for complex cases.

Our vetted London network

A small panel of fertility units, we picked them.

HFEA-licensed units across London where time-lapse is embedded in standard practice — introductions made privately, once we understand your case.

Selection criteria

How we choose every fertility unit in our network.

A modern London embryology laboratory with time-lapse incubators
Consultant embryologists
  • Consultant embryologists using validated time-lapse platforms (EmbryoScope, Geri, MIRI)

  • Morphokinetic annotation to ESHRE / Alpha consensus definitions

  • KIDScore or equivalent validated selection algorithms

  • Onward pathway to PGT, endometrial receptivity testing and MDT review

Red flags

When your cycle needs specialist input.

These are the patterns where time-lapse alone is not enough — a reproductive-medicine consultant should be involved in planning.

  • Recurrent implantation failure

    Three or more failed transfers of good-quality embryos warrant specialist reproductive-medicine review.

  • Recurrent miscarriage

    Two or more consecutive pregnancy losses justify parental karyotyping, thrombophilia and uterine assessment.

  • Poor ovarian response

    Low oocyte yield despite maximal stimulation calls for revised protocols and mitochondrial-support discussion.

  • Advanced maternal age

    Age above 38 significantly raises aneuploidy risk — PGT-A alongside time-lapse should be discussed.

  • Male factor infertility

    Severe oligo-, astheno- or teratozoospermia warrants ICSI, sperm DNA fragmentation testing and andrology review.

  • Post-cancer fertility

    Fertility after chemotherapy or radiotherapy requires oncofertility specialist input and, often, cryopreserved gametes.

  • Endometriosis

    Moderate-to-severe endometriosis affects oocyte and endometrial quality — a specialist pathway is warranted.

  • Post-COVID fertility

    Concerns about persistent effects on ovarian reserve, sperm parameters or thrombosis risk merit dedicated review.

  • PGT-M for genetic condition

    Known monogenic disorders in the family require specialist genetic counselling and PGT-M planning.

Reading your report

A morphokinetic report can look intimidating. It isn’t.

Whatever the finding, the report keeps to the same four parts.

A consultant embryologist reviewing time-lapse embryo footage on a clinical workstation at a UK private clinic

A quiet reminder

The report is written for your fertility team, not for you — and that’s normal.

If you would like us to talk you through it before your follow-up, just ask.

  1. 01 Header

    Cycle summary and indication

    Your details, cycle number, protocol used and the reason time-lapse imaging was performed.

  2. 02 Culture

    Platform and culture conditions

    Time-lapse system used, culture media, oxygen tension and duration of monitoring.

  3. 03 Findings

    Morphokinetic parameters and grading

    Timing of each developmental milestone, morphological grade, KIDScore ranking and any abnormal cleavage patterns.

  4. 04 Impression

    Selection and plan: read this first

    Which embryo has been selected, why, and the planned transfer strategy — read this first.

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Cover depends on your policy and clinic; we confirm with your insurer before booking.

Frequently asked

Everything we get asked about time-lapse imaging.

Quick answers on success rates, safety, PGT comparison, KIDScore and where to have it.

  • What is time-lapse imaging in IVF?

    Time-lapse imaging is continuous embryo monitoring inside a specialist incubator — such as EmbryoScope, Geri or MIRI — that captures an image of every embryo every few minutes. It gives embryologists a full developmental record instead of a series of static daily snapshots.

  • Does time-lapse improve IVF success rates?

    Evidence suggests that time-lapse improves embryo selection and reduces embryo disturbance, but the impact on live-birth rates versus standard culture is modest and remains debated. It is best considered a selection aid rather than a treatment in its own right.

  • Is time-lapse imaging safe for embryos?

    Yes. The imaging uses low-intensity red light in extremely short exposures and the incubator maintains a stable environment. Time-lapse arguably reduces stress on embryos by removing the need for repeated daily assessments outside the incubator.

  • How does time-lapse compare to PGT?

    Time-lapse assesses developmental kinetics and morphology, while PGT tests the embryo’s chromosomes or specific genes. They answer different questions and are frequently used together for the most informed selection.

  • What is KIDScore?

    KIDScore (Known Implantation Data Score) is a validated algorithm developed for time-lapse platforms. It ranks embryos on their morphokinetic profile against implantation-linked reference data.

  • Which clinics offer time-lapse imaging?

    Most established UK fertility units now offer time-lapse imaging on at least one platform. We match you to a clinic where time-lapse is embedded in standard practice — not an add-on billed on top.

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In practice, in London

Getting timelapse imaging sorted in London, without the guesswork

With timelapse imaging, the London question is usually about report turnaround and the radiologist reading it — not whether the scan is available. Waiting lists on the NHS for timelapse imaging vary widely by borough and by how the GP letter reads. Privately in London, we can normally offer a slot inside the same week, sometimes within 48 hours if there’s a cancellation. The difference isn’t clinical quality — the consultants are frequently the same faces you’d see on the NHS — it’s the calendar.

A private timelapse imaging pathway in London usually looks like this: an initial consultation, any diagnostics booked at a nearby facility (most within Zone 1 or 2), and a written report sent to you and your GP within a few days. The consultants we work with hold NHS posts alongside their private lists, which keeps the standards consistent across both settings. For timelapse imaging specifically, the difference between a routine report and a sub-speciality read is where private care earns its keep.

Where a good concierge earns its keep is in the matching. There are dozens of consultants in London who see timelapse imaging — but not all of them are the right fit for every case. We narrow it down based on subspecialty, insurer coverage, the specific question being asked, and whether continuity into treatment matters. The right first appointment saves you from repeating yourself later.

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