Preventive medicine · London
Longevity and biomarker clinic, honest and evidence-first.
A comprehensive baseline of the biomarkers, imaging and functional tests that actually change management, and a plain-English plan that separates preventive medicine from the marketing that surrounds it.
Why patients choose us
- 01
Evidence-first, not marketing-first
We separate biomarkers that change management (ApoB, Lp(a), hsCRP, VO2 max, grip strength, DEXA, BP, HbA1c) from cosmetic testing that changes nothing.
- 02
A physician-led programme, not an IV bar
Longevity medicine is preventive cardiology, endocrinology and sports medicine. We steer you clear of unregulated peptide clinics and drip lounges.
- 03
Independent, and free
We are paid by no clinic, so the recommendation between an executive assessment, a full concierge programme or a single-shot workup is impartial.
Indicative pricing
What a private longevity workup actually costs.
Ranges across the London centres we work with. We come back with a firm quote and two or three options once we know your goals.
In short
A serious baseline: £2,500 to £8,500, with an annual review from £1,800.
| Programme | Indicative range | Typical duration | Turnaround |
|---|---|---|---|
| Focused baseline (bloods + DEXA + calcium score + consult) | £2,500 to £4,000 | Half day | 1 to 2 weeks |
| Comprehensive workup (adds CPET, WatchPAT, cognitive, MRI selective) | £4,500 to £8,500 | Full day | 2 to 3 weeks |
| Annual re-assessment | £1,800 to £4,500 | Half to full day | 1 to 2 weeks |
| Concierge programme (12 months, physician + team on call) | £8,500 to £28,000 | Ongoing | Continuous |
| Genetics add-on (APOE, targeted panels) | £350 to £1,200 | Postal or in-clinic | 3 to 6 weeks |
| Second-opinion review of prior workup | £250 to £500 | 45 min | 48 hours |
Prices vary by centre, by which imaging is included, and by whether you want a one-shot workup or a continuous concierge programme with quarterly touchpoints and unlimited physician access.
The journey
From first call to annual review - what happens, in order.
A dietitian, exercise physiologist and sleep coach in the same team as your physician. Optional psychology when it earns its place.
- 01
Before
A short intake and goals call
Family history, current medications, symptoms and what you actually want from the programme: prevention, symptom work-up, or performance optimisation.
- 02
Before
We match you to a physician
A preventive cardiologist, endocrinologist or lifestyle medicine physician depending on your risk profile. Concierge or single-visit format.
- 03
Before
Fasting bloods and pre-visit imaging
Comprehensive panel drawn locally. Coronary calcium score and DEXA scheduled before the clinic day so results are on the table when you sit down.
- 04
On the day
The assessment day
Physical exam, CPET with VO2 max, grip strength, gait speed, WatchPAT for the following night, cognitive baseline, and a two-hour consultation.
- 05
On the day
Whole-body MRI (selective)
Offered when the family history or symptom picture supports it. We are honest about incidental findings and the follow-up cost they can trigger.
- 06
After
Written plan and shared decisions
A ranked list of what matters: lipids, blood pressure, glycaemia, cardiorespiratory fitness, strength, sleep, bone density and mood. Interventions ordered by evidence.
- 07
After
Quarterly touchpoints and annual review
Nurse-led quarterly check-ins on adherence and side effects. Dietitian, exercise physiologist and sleep coach on call. Full re-assessment at 12 months.
What we measure
The tests that change management - and the ones that do not.
A clear split between high-yield preventive medicine and biomarker theatre. We are happy to tell you when a test is a nice number but not a decision.
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Lipid subfractions with ApoB and Lp(a)
ApoB is a better predictor of cardiovascular events than LDL alone. Lp(a) is measured once in a lifetime and changes who needs early, harder lipid lowering.
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Insulin resistance panel
Fasting insulin, HOMA-IR and HbA1c pick up dysglycaemia years before a formal diabetes diagnosis, opening the door to earlier lifestyle and pharmacological action.
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Cardiorespiratory fitness (VO2 max)
One of the strongest mortality predictors known. A formal CPET gives you a number, a percentile for your age and sex, and a training zone to work with.
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Grip strength and gait speed
Cheap, boring and predictive. Low grip strength and slow gait speed track all-cause mortality more reliably than most exotic biomarkers.
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DEXA for body composition and bone density
Visceral fat, lean mass and T-scores. Catches osteopenia and sarcopenia early, when resistance training, protein intake and, if needed, therapy can still change the trajectory.
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Coronary artery calcium score
A low-dose CT that quantifies coronary plaque. A zero score in mid-life is reassuring; a raised score reclassifies your risk and often adds a statin or PCSK9 inhibitor.
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Sleep study (WatchPAT for OSA)
Undiagnosed obstructive sleep apnoea drives hypertension, atrial fibrillation and daytime cognitive decline. A one-night home study is a high-yield, low-hassle test.
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Where we say no
NAD+ IV drips, unregulated peptides, telomere length testing and most direct-to-consumer polygenic risk scores have thin evidence. We will tell you honestly.
Programme components
Bloods, imaging, function, sleep, cognition, genetics.
The full menu. Not every patient needs every item - a good programme is the one that is right-sized for your risk profile and goals.
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Comprehensive bloods
Lipids with ApoB and Lp(a), fasting insulin, HOMA-IR, HbA1c, CMP, hsCRP, homocysteine, uric acid, ferritin and iron studies, vitamin D, B12 and folate, TFT with T3, sex hormones, DHEA, cortisol, IGF-1, SHBG, PSA, coagulation, urine ACR and cystatin C.
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Imaging
Coronary calcium score for cardiovascular risk reclassification. DEXA for body composition and osteoporosis screening. Carotid intima-media thickness on selected patients. Whole-body MRI only when clinically indicated.
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Fitness and function
CPET with VO2 max, grip strength dynamometry and gait speed. These functional measures often outperform blood-based biomarkers for predicting how the next decade will actually go.
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Sleep and cognition
WatchPAT home study for obstructive sleep apnoea. A structured cognitive baseline so future changes are measured against your own starting point rather than a population average.
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Genetics (used sparingly)
APOE genotype where the family history or symptom picture warrants it. Polygenic risk scores discussed but framed honestly: research-grade signal, limited clinical action for most people today.
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Interventions we actually use
Mediterranean-pattern eating, resistance and aerobic training, sleep hygiene, stress work. Targeted supplements: vitamin D, omega-3, creatine and 1.4 to 1.8 g/kg protein. Statin, PCSK9, GLP-1 or HRT where clearly indicated.
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Interventions we are cautious about
Metformin, rapamycin and NAD precursors are interesting research topics. We will discuss them, but we will not prescribe outside licence on the basis of hope.
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Second-opinion review
You already have a stack of results from an executive health day or a direct-to-consumer test. We will read it critically and tell you what to act on and what to ignore.
Our vetted London network
Physician-led programmes, not brand-led drip lounges.
Cleveland Clinic London Executive Health, HCA Wellington Executive Health, London Medical Longevity and selected consultant-led practices. Randox Health for baseline biomarker panels.
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Physician-led programmes with a preventive cardiology or endocrinology lead, not brand-led wellness offerings
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CQC-regulated facilities with proper laboratory partners and radiology governance
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Access to lifestyle medicine, dietetics, exercise physiology, sleep medicine and clinical psychology in one team
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Honest incidental-findings pathways for whole-body imaging and coronary calcium scoring
Honest limits
What we say no to, and why.
A serious longevity programme is defined as much by what it declines as by what it offers. Here is where we hold the line.
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Incidental findings from whole-body MRI
Up to 15 to 30% of scans flag something that turns out to be benign. Consent covers the downstream cost, anxiety and follow-up scans this can generate.
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Testosterone and HRT are prescribed for symptoms
Not for a number on a page. We use guideline-based thresholds and reserve therapy for symptomatic patients with confirmed low levels.
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Rapamycin and metformin: research use only
Neither is licensed for longevity in the UK. Any off-label discussion is framed as experimental, with the risks and unknowns explained in writing.
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NAD+ IVs and IV vitamin drips
Evidence for meaningful longevity benefit is weak. We do not offer them as part of a serious preventive programme.
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Peptides are largely unregulated
Injectable peptides sold online sit outside the MHRA framework. Purity, dose and safety data are usually unknown. We do not prescribe them.
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Coronary calcium score and radiation
A low-dose CT (around 1 mSv). Worth it once for risk reclassification in the right patient. Not a screening tool for the worried well.
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Bloods can be over-interpreted
A borderline result on a large panel is common and often meaningless. We interpret the panel as a whole, in the context of your history and exam.
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Polygenic risk scores
Useful for research and for a small number of clinical decisions. For most people they add uncertainty without changing what we would already recommend.
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Data and privacy
Genetic and detailed biomarker data need proper stewardship. Ask where results are stored, who can access them and what happens if you leave the programme.
Reading your report
Your longevity report in four parts. Read the last one first.
A shared decision-making document you can hand to your GP, not a wellness dashboard.
- 01 Header
Your risk profile in one page
Cardiovascular, metabolic, bone, cognitive and cancer-screening risk summarised in a single view, with percentile comparisons for your age and sex.
- 02 Findings
What actually needs action
A short list. Usually blood pressure, lipids with ApoB and Lp(a), HbA1c and insulin, VO2 max and grip, DEXA, sleep and mood. Anything outside this list is context.
- 03 Plan
Interventions ordered by evidence
Lifestyle first, then targeted supplements, then medications with clear indications. Anything experimental clearly labelled as such, with a proper conversation attached.
- 04 Impression
What we monitor and when
Which markers we recheck at 3, 6 and 12 months, and which we leave alone. Read this section first so you know what the next year of the programme will look like.
Ready when you are
A serious preventive programme, matched to your risk profile.
Tell us your goals, family history and any existing results. We come back within one working day with two or three programme options across our London network - honest about what will change management, and what will not.
Recognised by major UK insurers
Preventive workups are typically self-funded. Some symptomatic investigations within the assessment may be covered by insurance.
Frequently asked
Everything we get asked about longevity clinics.
Honest answers on evidence, cost, whole-body MRI, peptides and NAD.
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Does a longevity clinic actually add years to my life?
Honestly, no clinic can promise that. What a good preventive programme does is push a small number of high-evidence levers: lower ApoB and blood pressure, treat sleep apnoea, raise VO2 max and strength, protect bone, screen appropriately, and treat mood and sleep. That combination shifts hazard curves for cardiovascular disease, dementia and frailty. The rest is atmosphere.
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Which biomarkers actually change what you do?
ApoB and Lp(a) change lipid management. hsCRP nudges risk stratification. HbA1c, fasting insulin and HOMA-IR change nutrition and drug decisions. VO2 max, grip strength and DEXA change the exercise prescription. Blood pressure trumps almost everything. Most of the rest is context, not a decision point.
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What about NAD IVs, peptides, rapamycin and metformin?
NAD IV drips have weak evidence for meaningful longevity benefit. Injectable peptides sold outside pharmacies are largely unregulated in the UK. Rapamycin and metformin are interesting research topics but neither is licensed for longevity. We will discuss all of them honestly and will not prescribe outside licence on the basis of hope.
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Is a whole-body MRI worth it?
Sometimes. In a symptomatic patient or one with a strong family history of a specific cancer it can be useful. As broad screening for well people it flags a lot of incidental findings, most of which are benign but all of which generate further scans, biopsies and anxiety. We only recommend it when the balance of benefit and harm makes sense for you.
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How much does a proper programme cost?
A focused baseline with bloods, DEXA, coronary calcium score and a consultation runs £2,500 to £4,000. A comprehensive workup adding CPET, sleep and cognitive testing and selective MRI is £4,500 to £8,500. Annual maintenance is £1,800 to £4,500. Full concierge programmes with continuous physician access run £8,500 to £28,000 a year.
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Which London centres do you work with?
Cleveland Clinic London Executive Health, HCA Wellington Executive Health, London Medical Longevity, and select physician-led practices. Randox Health is useful for baseline biomarker testing. We match you to the right one for your risk profile and budget rather than the one that pays the loudest for referrals.
Related treatments
Looking for something else?
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Executive health assessment
A one-day health MOT for busy professionals.
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Epigenetic age testing
Biological versus chronological age, honestly framed.
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Prenuvo full-body MRI
Whole-body screening MRI, with a candid view on incidental findings.
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Peptide therapy programme
What peptides can and cannot do, with UK regulatory context.
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Testosterone replacement
For symptomatic, confirmed low testosterone.
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Menopause blood panel
A structured hormone and cardiometabolic panel around menopause.
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NAD+ IV therapy
Where the evidence sits, and where it does not.
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Send Enquiry
Tell us your goals and we come back within a working day.
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