Regenerative dermatology · UK
Skin optimisation - regenerative dermatology, done properly.
PRP, polynucleotides, skin boosters and biostimulators - prescribed as a plan by a consultant dermatologist, not sold as a menu. Evidence-based combinations for the skin you actually have.
Why patients choose us
- 01
Consultant dermatology behind every injector
Every plan is prescribed by a GMC dermatology consultant. Injectors deliver under that plan - not the other way round.
- 02
Evidence-based sequencing
PRP, polynucleotides, boosters, biostimulators and topical retinoids sequenced by evidence - not by whatever the clinic represents this month.
- 03
Independent, and free
We are paid by no clinic, so the recommendation is impartial and costs you nothing.
Indicative pricing
What skin optimisation costs in the UK.
Indicative ranges across our vetted UK partners. Send the details and we quote firm figures across two or three options, with cover checked.
In short
A three-session polynucleotide course for the mid-face and under-eyes: £1,050–£1,800, across 3–4 weeks apart.
| Procedure | Indicative range | Typical duration | Turnaround |
|---|---|---|---|
| PRP facial (single session) | £350–£650 | 45–60 min | Same visit |
| PRP course of three sessions | £950–£1,650 | 45–60 min each | 3–4 weeks apart |
| Polynucleotides single session | £380–£650 | 30–45 min | Same visit |
| Polynucleotides course of three | £1,050–£1,800 | 30–45 min each | 3–4 weeks apart |
| Hyaluronic acid skin booster | £280–£550 per session | 20–30 min | Same visit |
| Biostimulator injectable (single area) | £450–£950 | 30–45 min | Same visit |
| Combined protocol consultation | £220–£380 | 30–45 min | Same visit |
Prices vary by product (PRP, polynucleotides, boosters, biostimulators), area treated and session count. Combined protocols and biostimulators sit at the top of the range.
The problem
A plan for your skin, not a product for your face.
Skin optimisation is where aesthetic clinics quietly over-sell - one product for every patient, no evidence-based sequencing, and no medical dermatology behind the injector.
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A plan, not a product
A single product will not do what a sequenced protocol can. We prescribe the plan first, deliver the products second.
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Evidence, not marketing
Some products are well-studied (PRP, polynucleotides in specific formulations). Some are not. We say which is which.
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Honest expectations
Regenerative treatments improve tissue quality. They do not replace laser resurfacing for scars, or surgery for laxity. We say so before you spend.
The journey
From enquiry to recovery - what happens, in order.
One team from first message through the procedure, results and follow-up.
- 01
Before
You send photographs and concerns
Photographs of the concern, prior treatments, and what "better" looks like for you.
- 02
Before
We propose a plan
Within one working day: a sequenced protocol of PRP, polynucleotides, boosters or biostimulators - with evidence, cost and cadence.
- 03
Before
Consultation and prescription
Consultant dermatology assessment, photographs, and prescription of the protocol. Numbing cream applied before treatment.
- 04
On the day
Treatment
20–60 minutes depending on product and area. PRP includes a blood draw and centrifugation on site.
- 05
On the day
Aftercare
Cool packs, no make-up 24 h, no exercise or alcohol 24–48 h, sunblock the next day. Written aftercare in hand.
- 06
After
Session review
Photographic review at 3–4 weeks before the next session. Adjustments made where response is less than expected.
- 07
After
Maintenance
Once the initial course is complete, maintenance every 4–6 months, layered with medical dermatology and laser as appropriate.
When it helps
When skin optimisation is the right step.
The concerns where regenerative injectables improve tissue quality - and the ones where topical, laser or surgical treatment is a better answer.
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Early photoageing
Loss of glow, fine dehydration lines, mild texture changes - often the best regenerative response.
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Under-eye quality
Fine crêpiness and dullness under the eye - polynucleotides and PRP suit this area.
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Peri-oral fine lines
Small lines around the mouth from expression and sun - combined boosters and biostimulators.
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Neck and décolletage
Sun damage and thinning skin - where surgery and laser risks scarring, boosters and polynucleotides help texture.
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Hands
Sun-damaged, thin skin over the hands - biostimulators and boosters improve skin quality.
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Hair thinning
Early androgenetic alopecia and telogen effluvium - PRP is an adjunct with modest evidence.
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Post-laser or post-surgery recovery
Adjunctive PRP and polynucleotides can shorten recovery from resurfacing or reconstructive work.
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Red flag: pigmented lesion or active infection
Never inject into active herpes, active acne pustules or through an undiagnosed pigmented lesion.
Options
Options - combined into a protocol, not sold à la carte.
What each modality does, its evidence, and where it belongs in a sequenced plan.
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Platelet-rich plasma (PRP)
Prepared from your own blood - growth factors delivered by microinjection or with microneedling.
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Polynucleotides
Salmon-DNA fragments injected superficially - evidence for hydration, texture and under-eye quality.
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Hyaluronic acid skin boosters
Non-cross-linked hyaluronic acid injected superficially for hydration and skin quality.
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Amino-acid mesotherapy
Cocktails of amino acids, vitamins and antioxidants - modest evidence, usually part of a wider plan.
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Collagen-stimulating biostimulators
Poly-L-lactic acid, calcium hydroxylapatite and hybrid products - stimulate collagen over months.
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Microneedling with topical serums
Fine-needle induction with PRP or polynucleotide serums for even delivery.
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Combined protocols
Sequenced PRP, polynucleotides and boosters through a course - not delivered on the same day.
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Adjunct to laser and topical retinoids
Regenerative injectables sit best alongside a topical regime (retinoid, vitamin C, SPF) and, where indicated, laser.
Our vetted UK network
A small panel of consultants, we picked them.
Consultants across London and the major UK cities. Introductions are made privately, once we understand your case.
Selection criteria
How we choose every clinician in our network.
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Consultant dermatology prescribes every protocol
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Product provenance verified - CE-marked, batch-recorded, cold-chain compliant
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Written treatment plan and audited photographs at every session
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Independent - no in-house product-brand incentives
Safety and recovery
What to expect afterwards - honestly.
Regenerative injectables are safe in trained hands. What matters is technique, product provenance, and honesty about what these treatments do and do not deliver.
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Bruising and swelling
Common and short-lived - 24–72 hours. Ice and avoiding blood-thinners help.
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Infection
Rare with sterile technique. Signs to call about: spreading redness, throbbing pain, fever.
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Allergic reaction
Very rare with PRP (autologous) and polynucleotides. More possible with mesotherapy cocktails - allergy history matters.
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Nodules and lumps
Rare with skin boosters and biostimulators - massage and, occasionally, hyaluronidase for HA products.
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No improvement
Some patients respond less than expected. We photograph and honestly reassess - not simply upsell.
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Regenerative is not resurfacing
These treatments do not replace laser for acne scars or surgery for laxity. We say so before recommending a course.
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Not for pregnancy or active infection
Avoided in pregnancy, breastfeeding, active skin infection, active herpes and active cancer.
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Autologous PRP safety
PRP uses your own blood - very low risk. Provenance issues only arise if third-party products or additives are used.
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Red flags after treatment
Sudden pain, spreading redness, vision change (rare, but relevant with any facial injectable), or blanching of the skin needs immediate contact.
Reading your notes
Your notes in four parts. Read the last one first.
The letter you receive from the consultant keeps to the same shape.
- 01 Assessment
Skin quality and concerns
Baseline photographs, Fitzpatrick type, concerns and previous treatments.
- 02 Protocol
Products and cadence
Which products at which sessions, and why they are sequenced that way.
- 03 Response
Session-by-session outcome
Photographic outcomes across the course and honest response reads.
- 04 Impression
Maintenance and integration
Read this first: maintenance interval, integration with laser and topical regime, and long-term expectations.
Recognised by major UK insurers
Skin optimisation is cosmetic and not covered by insurance. PRP for medical hair loss is sometimes considered - we check case-by-case.
Frequently asked
Everything we get asked about skin optimisation.
Quick answers on PRP, polynucleotides, downtime, evidence and cost.
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What is skin optimisation, and how is it different from a facial?
Skin optimisation is regenerative dermatology delivered as a sequenced protocol - PRP, polynucleotides, hyaluronic-acid boosters and biostimulators, prescribed by a consultant dermatologist. It is not a facial. It is a medical treatment with expected outcomes measured on photographs, not a spa experience.
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What is PRP, and what does it actually do?
Platelet-rich plasma is prepared from your own blood by centrifugation. The concentrated plasma is injected superficially or delivered with microneedling. Evidence supports modest improvements in skin quality, mild rhytids and post-procedure recovery. It is not a substitute for laser resurfacing.
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What are polynucleotides?
Injectable fragments derived from salmon DNA. They act as biostimulators of fibroblasts, with reasonable evidence for improved hydration, texture and under-eye skin quality. A course of 3–4 sessions is standard.
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How much downtime is there?
PRP and polynucleotides: mild swelling and small bruises for 24–72 hours. Skin boosters: injection bumps that settle in a day. Biostimulators: some tenderness and swelling for 1–3 days. All treatments allow return to normal social activity within a few days.
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How is this different from your Skin Health service?
Skin Health is a broad consultant dermatology service - mole checks, medical dermatology (acne, rosacea, eczema), prescriptions and surveillance. Skin Optimisation is specifically the regenerative injectable protocol - PRP, polynucleotides, boosters, biostimulators - prescribed by the same consultant team but delivered as a separate, sequenced course.
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How much does skin optimisation cost in the UK?
A PRP session is £350–£650, with a three-session course £950–£1,650. Polynucleotides are £380–£650 per session or £1,050–£1,800 for three. Hyaluronic-acid skin boosters are £280–£550 per session. Biostimulator injectables run £450–£950 per area. Combined consultation is £220–£380.
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