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Bioregenerative aesthetics · London

Rejuran salmon DNA injections, by an experienced injector.

The Korean PDRN polynucleotide, done properly. Healer for skin quality, I for the peri-orbital area, S for atrophic scars, HB when you want hydration in the same visit.

A stethoscope on a clinical desk

Indicative pricing

What Rejuran costs in London.

Indicative ranges across the London clinics.

Treatment Indicative range
Rejuran Healer (face, per session) £280–£450
Rejuran Healer, course of 3 £850–£1,400
Rejuran I (peri-orbital, per session) £380–£650
Rejuran S (acne scar, per session) £280–£450
Rejuran HB (hydration + HA, per session) £320–£500
Consultation and skin assessment £150–£250

When it helps

The concerns Rejuran genuinely improves.

It is a bioregenerative injection, not a filler. Rejuran changes the quality of the skin. If you need volume, we will say so.

  • Dull, crepey, thin skin

    The classic Healer indication. Gradual dermal thickening and a smoother light-reflective surface over 8 to 12 weeks.

  • Peri-orbital fine lines

    Rejuran I is formulated for the thin, mobile skin under the eyes. Not a filler and not for volume loss.

  • Atrophic acne scars

    Rejuran S targets rolling and boxcar scars, often combined with subcision or fractional resurfacing over a course.

  • Post-inflammatory hyperpigmentation

    Adjunct to a proper pigment protocol. Improves the surrounding skin quality that makes marks look worse.

  • Dry, dehydrated skin

    Rejuran HB pairs the polynucleotide with hyaluronic acid for a hydration boost alongside the regenerative signal.

  • Hair thinning (adjunct)

    Scalp Rejuran is used alongside PRP, exosomes or minoxidil as a supportive regenerative injection, not a stand-alone hair loss cure.

The Rejuran range

Four formulations, four jobs.

Compared to Plinest and Newest, Rejuran uses the same bioregenerative mechanism but a different source (Korean salmon PDRN) and a range built around specific concerns. Sits alongside Profhilo (thermally cross-linked HA bioremodelling), skinboosters (HA hydration) and fillers (volume).

  • Rejuran Healer

    The original PDRN skin-quality range. Micro-injections in a grid across the face for tone, texture and elasticity.

  • Rejuran I

    A finer formulation for the delicate peri-orbital skin. Softer bumps, faster settle, more forgiving of movement.

  • Rejuran S

    A denser gel-like preparation designed to sit under atrophic scars and lift them from below over a course of sessions.

  • Rejuran HB

    PDRN combined with hyaluronic acid. Adds an immediate hydration and light plumping effect to the bioregenerative signal.

Safety and downtime

What to expect, honestly.

A well-tolerated injectable with a short social downtime. The result is gradual, not instant.

  • Small bumps for 24–48 hours

    Rejuran leaves visible micro-blebs across the treated area that settle within a day or two. Plan around social events.

  • Bruising is common

    Peri-orbital treatment in particular can bruise. Avoid alcohol, aspirin and fish oil for 48 hours before if you are able.

  • Not an instant result

    This is a bioregenerative injection, not a filler. Meaningful skin-quality change appears at 8 to 12 weeks, after the full course.

  • Salmon allergy contraindication

    Rejuran is derived from salmon DNA. A confirmed fish allergy is a contraindication. Pregnancy and active skin infection are also.

  • Stack sensibly

    Rejuran combines well with Profhilo, skinboosters and microneedling on separate visits. We space treatments so nothing competes.

  • Aftercare

    No make-up for 12 hours, no sauna, gym or sun beds for 48 hours, and mineral SPF daily. Simple, and it matters.

Frequently asked

Everything patients ask about Rejuran.

  • What is Rejuran and how is it different from a filler?

    Rejuran is a polynucleotide injectable made by Pharma Research Products in Korea. It is derived from salmon DNA (a fragment called PDRN, or polydeoxyribonucleotide) and is injected in a grid pattern into the deep dermis. Unlike a hyaluronic acid filler, it does not add volume. It signals your skin to repair, so the result is improved skin quality over 8 to 12 weeks rather than an immediate lift.

  • How is Rejuran different from Plinest, Newest or other polynucleotides?

    Plinest and Newest are Italian polynucleotide brands (Mastelli, Priama) that work through the same bioregenerative mechanism. The main differences are the source (Italian trout gonads versus Korean salmon sperm), molecular weight, concentration and licensed indication. Clinical results are broadly comparable. Rejuran has more brand recognition thanks to Korean K-beauty demand, and the range (Healer, I, S, HB) is targeted at specific concerns.

  • How many sessions will I need and how often?

    The standard face course is 3 sessions spaced 3 to 4 weeks apart, followed by a top-up every 6 to 12 months. Scar and peri-orbital protocols sometimes extend to 4 sessions. Your injector will confirm at the consultation based on skin thickness, age and the concern being treated.

  • What does it cost in London?

    A single Rejuran Healer session for the face is £280 to £450, and a course of three is £850 to £1,400. Rejuran I for the eye area runs £380 to £650 per session because the technique is more demanding. Rejuran S for scars is £280 to £450 per session. Prices vary by clinic tier and injector.

  • Where in London is Rejuran done well?

    Cadogan Clinic, EF MEDISPA, Waterhouse Young, PHI Clinic and Young LDN all run experienced Rejuran lists. For peri-orbital Rejuran I we specifically recommend Dr Sabrina Shah-Desai, an oculoplastic surgeon whose eye-area work is a benchmark.

  • Is there any real downtime?

    The small injection bumps are the main issue. They flatten within 24 to 48 hours. Peri-orbital work bruises more often than the cheeks. Most patients treat on a Thursday or Friday and are camera-ready by Monday. There is no peeling and no need to hide indoors.

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